DCA dosage and usage

 

1. DOSAGE

Recommended DCA daily dose is 20 mg/kg daily (milligrams per human body kilogram per day).
Calculation of dosage for a particular person is simple: just multiply your weight by 20 mg/kg and you will get daily DCA dose in milligrams.

For example - if the person weighs 75 kg:
75 kg x 20 mg/kg = 1500 milligrams daily = 1.5 grams of DCA daily (5 capsules of 333 mg or 3 capsules of 500 mg)

The weight of the person should be taken excluding overweight.

MINIMAL DOSE
Minimal therapeutically effective DCA daily dose is two times smaller - 10 mg/kg daily. Smaller amount is not recommended as the drug may have little to no effect.

MAXIMAL DOSE
In case there are no side effects, DCA dosage may be increased to 30-40 mg/kg daily.
In case of strong side effects daily dose should be reduced to 10-20 mg/kg daily.

2. MEASURING DCA POWDER

The most accurate way to measure DCA powder is by water solution. It is best to prepare a solution containing 0,1 g of DCA powder in 1 ml of water solution.

1. Put 25 grams of DCA into 250 ml bottle (alternatively 50 grams into 500 ml, or 100 grams into 1000 ml). WARNING: remove and dispose of the desiccant packet, if there is one inside.
2. Pour cool distilled water till it reaches the 250 ml point.
3. Close the bottle and shake it until the powder dissolves.
4. This way 1 ml of solution will hold 0,1g of Sodium Dichloroacetate
1 milliliter DCA solution = 0,1 gram powder DCA

DCA solution, ml 1 2 3 4 5 6 7 8 9 10
DCA powder, g 0,1 0,2 0,3 0,4 0,5 0,6 0,7 0,8 0,9 1,0

3. DCA SCHEDULE

DCA should be taken 2 times a day with food. One half in the morning, the second half in the evening.

For example, if a person weights 80 kg and takes 2 grams (6 capsules) daily, he should take 1 gram (3 capsules) with breakfast and 1 gram (3 capsules)  with dinner.

During the first week of the treatment take smaller doses:

Day % of daily dose
Day 1 25%
Day 2 50%
Day 3 75%
Day 4 75%
Day 5 75%
Day 6 Break
Day 7 Break

If using DCA doesn‘t cause any unwanted side effects, next week start taking the full dose.

There are two known schemes for DCA usage:

A) Take full daily doses of DCA for five days straight and then take a break for two days. Repeat this routine every new week. (old way)

B) Take full daily doses of DCA every day for two weeks and then take one week off. This scheme could be more beneficial when seeking a better antitumor effect. (new way)

4. THE DURATION OF TREATMENT

Best results are to be expected in stage 1, 2 and 3 cancer.

STAGE 1 - 2:

  • Usually about 2 - 3 months, depending on the results.
  • Take scans and tests often to monitor your cancer.
  • Recurrence prevention: in case of remission, it is recommended to take DCA periodically (for about 6 weeks every 18 months or so). Tests should be taken, and, if there is a need, the frequency of DCA treatment may be increased.

STAGE 1, 2 or 3, IN CASE OF SURGERY WHERE ALL OR MOST OF THE TUMOR IS REMOVED:

  • About 6 weeks before surgery (to localize the tumor) and about 8 weeks after (to prevent metastasis).
  • Take scans and tests often to monitor your cancer.
  • Recurrence prevention: in case of remission, it is recommended to take DCA periodically (for about 6 weeks every 18 months or so). Tests should be taken, and, if there is a need, the frequency of DCA treatment may be increased.

STAGE 3:

  • Usually about 3 - 4 months, depending on the results.
  • Take scans and tests often to monitor your cancer.
  • Recurrence prevention: in case of remission, it is recommended to take DCA periodically (for about 6 weeks every 3-6 months or so). Tests should be taken, and, if there is a need, the frequency of DCA treatment may be increased.

STAGE 4:

  • Take constantly. In case of positive results, depending on the situation, DCA may be taken in smaller doses and with longer breaks.
  • Take scans and tests often to monitor your cancer.
  • Healthy lifestyle is important.

5. SIDE EFFECTS

Side effects occur in about 45% of cases and are age-dependant (less expected in younger patients). They are reversible and should disappear shortly after stopping DCA treatment.

Neurological:

  • Most common - peripheral neuropathy (hand and feet numbness or stiffness, hand tremor, sometimes - pain in arms and legs).
  • Rare - light delusional behaviour and hallucinations.

Gastrointestinal:

  • Heartburn, nausea, vomiting, indigestion. Pantoprazole may be taken as treatment.

Detailed information about side effects.

6. WHAT SUPPLEMENTS TO TAKE

To reduce or prevent neurological side effects, these supplements may be taken:

  • VITAMIN B1 (Thiamine) - 50-300 mg daily (the most important supplement to reduce the chance of neuropathy. Vitamin B1 also provides additional anticancer properties)
  • ALFA-LIPOIC ACID - 200-500 mg daily (do not take with chemo, wait 1 week after; do not take with radiotherapy, wait 2 weeks after)
  • L-CARNITINE - 500-1500 mg daily

You may also take the supplements that help liver function:

  • SILYMARIN supplements (for example: Carcil)
  • PHOSPHOLIPIDS (for example: Essentiale forte)

Immunity boosters, other:

  • VITAMIN D3 - start taking 3000UI daily and check blood level of 25-hydroxy vitamin D levels every month. Change dosage to achieve stable vitamin D level in normal range (40-60 ng/ml or 100-150 nmol/l)
  • MULTIVITAMINS - make sure it does not contain copper
  • SEA BUCKTHORN OIL
  • SHIITAKE, REISHI and MAITAKE mushrooms

7. DCA AND CHEMOTHERAPY

For information about DCA interaction with specific chemotherapy drug, try searching the internet. Dcaguide.org will prepare more information on this subject in the future. It's worth noting that  clinics use this strategy and achieve satisfying results.

8. DCA AND RADIOTHERAPY

DCA may improve the effects of radiotherapy in some patients. Try searching on the internet for further information. Dcaguide.org will prepare more information in the future.

9. EFFECTIVENESS DEPENDING ON THE TYPE OF CANCER

It appears that DCA may have a positive effect on almost all types of cancer, though the effectiveness varies. Especially good response is observed in cases of: non-small cell lung cancer, breast cancer, colon and colorectal cancer, brain astrocytoma, glioblastoma, neuroblastoma, Non-Hodgkin's Follicular Lymphoma, prostate, ovarian and other cancers.

Best results are to be expected in cases of stage 1, 2 and 3 localized cancer.

10. DIETARY RECOMMENDATIONS

Try eating more fresh fruits and vegetables, avoid sweets and animal fats. We advise you to check the internet for more information on effective diets when treating cancer. Till we publish new information, we advise you to eat a healthy diet for your overall health since food has an effect on the progression of the disease.