Can DCA be taken while fasting ? Or is it better to wait until the fasting is done ? I‘m on a 30 day fast.
Q: Can DCA be taken while fasting ? Or is it better to wait until the fasting is done ? I‘m on a 30 day fast.Marek
A: Dear Marek,
thank you for your question. DCA can still be absorbed while you are fasting. However, if you take DCA in powder form, dissolve it into a solution, drinking it on an empty stomach may cause heartburn after a while. The stomach that has had no food for longer periods of time can get irritated really easily.
To avoid this, you should take Sodium dichloroacetate in a capsule form. This way it will be lighter on your stomach. Also, take lower doses when you’re on your fasting protocol. Taking 6,25-12,5 mg/kg daily should be great.
Is DCA successful in treating SCLC?
Q: Is DCA successful in treating SCLC (small cell lung cancer)? Wayne
A: Dear Wayne,
thank you for your email. We have heard reports about people that successfully stopped SCLC (small cell lung cancer) progression with the help of DCA. One of them is in remission till this day and is still taking Sodium dichloroacetate for prophylaxis. However, as you have probably heard, SCLC is a really aggressive cancer and it needs the best measures to fight this disease. This means that DCA alone could still not be enough.
If you haven’t received a lot of nerve damaging chemotherapy and do not suffer from current peripheral neuropathy, you can consider trying DCA alone or alongside other cancer treatments. Just please don’t stop your current health checkups by your doctor and follow his advice.
A recent study has shown that DCA works well in combination with fenbendazole. (Ref.) There is also a growing community, which uses fenbendazole alongside conventional or alternative therapy to treat their cancer. Fenbendazole can sometimes do wonders when treating lung cancer. Give it a try.
We advise you to try DCA in combination with fenbendazole for the best result. You can find more information on DCA usage here: DCA information.
More information on fenbendazole and its potential therapeutic benefits for oncological diseases can be found here: https://www.fenbendazole.org/. The rest of the information can be found on google by using the keywords ‘‘fenbendazole cancer“.
Hope this information helps.
I have an aunt with breast cancer IV. Can you inform me about the right products please?
Q: I have an aunt with breast cancer IV. Can you inform me about the right products please? Daniel
A: Dear Daniel,
thank you for your email. We understand that this is a really hard time for you and your family.
She should continue getting regular health exams by her oncologist as well as other doctors that are following her current situation. If your aunt is receiving any kind of therapy and it is not too heavy on her well-being, please continue doing that. The best results are achieved when you combine traditional and alternative medicine together.
To answer your question, there are a number of available options for people with metastatic breast cancer.
First of all, if she doesn’t have peripheral neuropathy or liver function impairment, she can consider taking DCA (sodium dichloroacetate). You can find all the information you need on this page: https://www.dcaguide.org/dca-information. You can also choose where you get your product from all the suppliers that we reviewed: https://www.dcaguide.org/suppliers. You will definitely find something that can suit your needs. DCA needs at least 4-6 weeks to start working.
Secondly, you could also use fenbendazole as a part of your anti-cancer protocol. There have been studies suggesting that DCA becomes even more potent when used in combination with fenbendazole: Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. Fenbendazole also works against breast and a big variety of other cancers by itself. You can find more about fenbendazole on this site: https://www.fenbendazole.org/.
Recently, we’ve heard reports that this medication can help people with breast cancer, stabilizing the disease or shrinking the breast tumors. Just please make sure that the relative doesn’t have any significant liver problems such as cirrhosis or jaundice prior to starting fenbendazole. As with DCA, you also need some additional time for fenbendazole to start working. It is usually about 6-8 weeks.
Last but not least, the third option that is quite similar to fenbendazole is niclosamide. It’s a new substance that the complementary cancer treatment community has been following closely. However, it’s still relatively young and needs more information on the exact mechanisms on tumors.
Nevertheless, please give a look at https://www.niclosamide.org/ and research any available data on its potential against breast cancer. It should be great when used in combinations with other anti-cancer regimens.
If she is currently receiving no angiogenesis inhibitors such as Bevacizumab (Avastin), your aunt can try Ammonium tetrathiomolybdate (TM). It is an anti-cooper agent that promotes survival in metastatic breast cancer. This molecule can be combined with DCA for better results. It should not be combined with chemotherapy. They had positive results in breast cancer patients in this clinical trial: Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases.
She should take 40 mg of TM three times per day with meals for about a week. Then later on she should lower the dose to 30 mg of TM three times per day with meals. The goal is to achieve serum ceruloplasmin levels of 5-15mg/dL and keep them that way. Without additional cooper ions, the cancer has lower chances of growing new blood vessels and expanding further.
Hope this gives some sort of guidance for your journey.
I live in Alberta, I can‘t seem to find Vitamin B1 or any of the other recommended supplements suggested. Does anyone know where I can get these from in Alberta Canada ?
Q: I live in Alberta, I can‘t seem to find Vitamin B1 or any of the other recommended supplements suggested. Does anyone know where I can get these from in Alberta Canada ? Debbie.
A: Dear Debbie,
thank you for your email. Unfortunately, we cannot recommend any specific brand of the protective supplements. You‘ll need to decide which kind suits your budget and needs the best.
Your best bet would be to use the Canadian Amazon shop to find these products. It’s up to you to make the decision on what you like and trust, we believe that there are many quality supplement brands out there.
1) Vitamin B1: https://www.amazon.ca/s?k=Vitamin+B1&ref=nb_sb_noss_2. (buy Benfotiamine if possible), 2) Alpha-lipoic acid: https://www.amazon.ca/s?k=Alpha+lipoic+acid&ref=nb_sb_noss_2., 3) Acetyl L-Carnitine: https://www.amazon.ca/s?k=Acetyl+L-Carnitine.&ref=nb_sb_noss.
Like mentioned previously, if you have the opportunity, try taking Benfotiamine as your primary choice of Vitamin B1. It seems to have a stronger neuroprotective effect than Thiamine against DCA adverse reactions. You will also need to take two times lower doses of Vitamin B1.
We are still going to give DCA as this is our last hope, but we are also going to give some vitamins specifically for the liver. Should we give these vitamins or not? Is there any recommended dosage for Silymarin?
Q: Cancer took the most part of the liver (3/4), but still not completely gone. We are still going to give DCA as this is our last hope, but we are also going to give some vitamins specifically for the liver. Should we give these vitamins or not? On your website, it seems like it is encouraged to give.
Is there any recommended dosage for Silymarin? I found this supplement below in Turkey, they recommend 1 capsule a day, and it has 80% Silymarin, but I couldn’t be sure if it is enough in our case. Kurtulus.
A: Dear Kurtulus,
thank you for reaching us out. Adult dosage in terms of hepatoprotection is 420 mg/day of Silymarin extract (standardized to 70-80% Silymarin). I would advise to take three 140 mg capsules a day. Take one with breakfast, second one with lunch and the last one with dinner.
You can also take Essential phospholipids (EPL) to help speed up liver recovery from light or heavy damage. The recommended dosage is 900-1800 mg/day. Take three 300 or 600 mg capsules daily with your meals.
These supplements are extremely safe and have virtually no drug interactions. They are also used in a healthcare setting to aid liver recovery. However, you need to take them at least 2-6 months straight for the effect to be evident.
You can take Silymarin and Essential phospholipids separately or together for swift and positive response. It‘s up for you to decide.
Can I order DCA directly from DCA-LAB? If so, how do I place an order?
Q: Can I order DCA directly from DCA-LAB? If so, how do I place an order? William.
A: Hello, William. If you want to order from DCA-LAB or other suppliers – please find their website links here:
You can also find them on Amazon:
Hope this is helpful.
I have not taken this supplement together with the DCA as an optional 3rd supplement. I have read that this acetyl L Carnitine could also cause weight loss. I would love to gain weight … Your opinion on this ?
I learned about your existence via the DCA company as I forwarded a question to them that they aren’t entitled to answer. I hope you might enlighten me on my query.
I had half a lung removed since being diagnosed with a lung tumour (Dec 2018). I refused chemotherapy, radiotherapy and started DCA as part of a natural alternative therapy via food and other healthy disciplines.
I have been taking DCA for 3 months now, my weight is 51 kg and I took one DCA tablet daily in the morning until a few weeks ago. To lower the side effect of trembling and coordination (I had some). I take benfotiamine (300mg/day) and Alpha lipoic acid 3x200mg/day.
My first scan at the beginning of April was clear the next one in July showed a lymph node 24mm in the top part lung, the doctor thought my cancer wanted to re-emerge in the lymph system. I’m not followed by an oncologist as he dropped my case since I refused chemo and radiotherapy. France is very traditional and even hostile towards my sort of attitude.
I have had no new scan since and carry on doubling the dose: one tablet in the morning, one tablet in the evening. Two weeks on and one week off. My monthly blood tests are rather very satisfying and carried out by my general practitioner.
I have not taken this supplement together with the DCA as an optional 3rd supplement. I have read that this acetyl L carnitine could also cause weight loss. I would love to gain weight … Your opinion on this ?
Thanks for whatever advice you can give and light you can shed on my query.
A: Dear Mrs. Josiane,
Thank you for your e-mail.
You can surely take the DCA protocol without Acetyl L-Carnitine (ALC). In our honest opinion, it is the least important neuroprotective supplement in comparison to Vitamin B1 and Alpha-lipoic acid. Nevertheless, there are some studies proving that Acetyl L-Carnitine could help avoiding DCA side effects of the nerve system. (Ref1.), (Ref2.), (Ref3.)
There is limited evidence that Acetyl L-Carnitine provides significant weight loss, in fact, there is still no significant evidence that it could cause measurable weight loss. There were no differences in weight loss between women who took ALC and those who didn‘t. (Ref.1) , (Ref2.)
Acetyl L-Carnitine is nothing to be afraid of. It is found in animal products and is consumed by people every day. If you are vegetarian, taking a little bit of Acetyl L-Carnitine could even prove beneficial for you since you get a reduced amount of it from your diet.
However, if you’re too uncomfortable consuming it, take smaller doses or avoid using it altogether. The stress and negative feelings that come with it are too big of a price to pay for the benefits.
On the other hand, if you feel more relaxed about Acetyl L-Carnitine – please take it as recommended in our articles or by your doctor.
We have been following people that are taking these supplements at least 3 years and we have never heard that L-Carnitine caused any problems.
I would like to discuss DCA treatment as soon as possible. My father has recurring Non-Hodgkin lymphoma – which is being treated with R-CHOP. I would like to discuss this with someone.
Q: I would like to discuss DCA treatment as soon as possible. My father has recurring Non-Hodgkin lymphoma – which is being treated with R-CHOP. After treatment, my dad experienced C.Diff and is now in the hospital. There are currently other complications and he has liver cirrhosis. R-CHOP is not the answer. We need to seek alternative solutions. I would like to discuss this with someone. Best, Inessa.
A: Hello, Inessa,
this is a rather difficult situation. On one hand, Sodium dichloroacetate can indeed be used to treat and control your father’s lymphoma. On the other hand, taking DCA while one has liver cirrhosis and poor liver function at home is unsafe. This is because Sodium dichloroacetate is metabolized in the liver and needs proper liver health to be properly digested.
Your best bet would be to take the lowest DCA dose possible (6.25 mg/kg daily) by yourself at home or to take him to a DCA clinic where he could receive DCA intravenously. Intravenous Sodium dichloroacetate causes far less side-effects and is tolerated better than oral DCA.
If you want a consultation with one of the best DCA specialists in the world – try reaching out Dr. Akbar Khan at Medicor Cancer. They can do telemedicine appointments or you can visit them in Canada.
Regarding DCA and Non-Hodgkin’s lymphoma, as you have already noticed – we have a big article on that:
DCA and Cancer: Non-Hodgkin’s lymphoma cured in 4 months (Case presentation). The main point of the paper is that one can achieve remission and keep cancer-free with the help of DCA. This is a real life example.
Please read the article carefully. After you’re finished reading it, you can read two studies that discuss this case in more details: 1) Non-Hodgkin’s Lymphoma Reversal with Dichloroacetate (Case Report), 2) Complete response with DCA in non-Hodgkin’s lymphoma after disease progression (Case report).
Last but not least, the Clostridium difficile infection could have been caused by the chemotherapy he received, antibiotics or compromised immune system. If he has C. difficile, he should be treated in the hospital by his physicians to avoid severe complications. Your doctor will prescribe vancomycin, fidaxomicin and / or metronidazole orally. He should also take as much fluids as possible to avoid shock. A diet that has low fiber and greens is also helpful, he should eat rice, bread, soup, fish or chicken etc. till he recovers.
My supplier was Pharmacy DCA for quick delivery from UK. I am thinking of DCA -LAB for the next shipment. Can you advise me please?
Q: I am suffering from prostate cancer stage 2 for 7 years. Started taking DCA 500mg 3 times a day for 6 weeks (at the end of the month). I will check my PSA on the 30th of August 2018. In case of a positive result, I want to continue the treatment for another 2 months. My supplier was Pharmacy DCA for quick delivery from UK. I am thinking of DCA -LAB for the next shipment. Can you advise me, please. Best regards, Roger.
A: Dear Roger,
unfortunately, prostate cancer affects a lot of men in the world. Gladly, there is plenty of research discussing the subject.
Firstly, you need to monitor your cancer treatment progress. Figure out whether the therapy that you‘re receiving at the moment and the DCA protocol are working. Please check your PSA levels and find out if it is increasing or decreasing. Repeat your PSA test once every 3 to 6 months.
A Computed tomography or Positron emission tomography (PET) imaging scans as well as intrarectal sonography could also be helpful in monitoring whether the treatment is working or not. If the tumor marker and the size of the tumors are stable or decreasing – continue what you‘re doing. If they are increasing – consider changing or adding something new to your regimen.
Also, please follow your doctor‘s advise as a primary guide. He‘s a healthcare specialist and understands your situation the best.
Regarding your question about the suppliers, we believe that DCA-Lab is a great brand that offers good customer service as well as delivery times. You can‘t go wrong by choosing them. Nevertheless, consider reading our detailed review on the most popular Sodium dichloroacetate suppliers: https://www.dcaguide.org/suppliers/dca-lab.
Fighting prostate cancer is a daunting task at first. However, you’ll quickly develop the habit of taking your personalized routine daily and finding out which options work the best for you. Another great addition to the DCA protocol is fenbendazole. Studies revealed that they both work complementary of each other. (Ref.)
We recommend adding fenbendazole to your protocol for even better results. It‘s a great combination with DCA, especially for prostate cancer. You can find out more information about this repurposed veterinarian drug for cancer at https://www.fenbendazole.org/.
Is your group still in existence? Do you have any information on DCA quality since 2018? Have you discovered who is behind “Certified DCA”, whether it is really a pharmaceutical grade product, and whether its purity is as they claim?
Q: Is your group still in existence? Do you have any information on DCA quality since 2018? Have you discovered who is behind “Certified DCA”, whether it is really a pharmaceutical grade product, and whether its purity is as they claim? Elizabeth
A: Dear Elizabeth,
thank you for your email. Yes, our group is still in existence. However, due to the Covid-19 pandemic, we have been less active lately. We are still following the global situation on DCA manufacturing. Unfortunately, a lot of Sodium dichloroacetate suppliers have remained completely the same or have taken a step back in terms of the quality of their services.
Many popular DCA suppliers have abandoned this molecule due to the recent inactivity of clinical trials with Sodium dichloroacetate. This was partly caused by the Corona virus pandemic, since all the attention and funding were redirected towards solving the Covid-19 crisis.
Nevertheless, the situation should come back to normal in half a year. We noticed that a lot of previously great DCA sellers have developed problems with their sites, customer service quality and delivering the products on time.
Regarding the claims by Certified DCA. Firstly, Sodium dichloroacetate is not registered as a licensed medicine, therefore a pharmaceutical grade product of DCA cannot officially exist. Such claims are false.
Secondly, the quality of their product has not changed since the last time we reviewed them. Therefore, we didn’t feel the need to update their product review.
Lately, their site has been down and it’s not possible to order a new batch of their production. We’ll try to check them whenever it will be possible.
Can I take DCA while getting chemotherapy? I get 140mg of Abraxane per week for breast cancer.
Q: Hello. Can I take DCA while getting chemotherapy? I get 140mg of Abraxane per week for breast cancer. Maricel
A: Dear Maricel,
Thank you for your question. Yes, you can try taking Abraxane or Paclitaxel with DCA on the following conditions:
• You currently do not suffer from pre-existing neuropathy, especially the one that was caused by previous chemotherapy,
• You take a 3 day break from DCA and Alpha-lipoic acid before Abraxane or Paclitaxel injection,
• You should resume DCA and Alpha-lipoic acid not sooner than 4 days after your last chemotherapy infusion,
• You should resume your daily Vitamin B supplementation as soon as you’re released from the healthcare setting,
There are studies, which prove that Sodium dichloroacetate can reverse the mitochondrial damage as well as dysfunction in Paclitaxel treated cancer cells. This reverses Abraxane/Paclitaxel drug resistance and makes the chemotherapy work more efficiently. On top of that, DCA itself causes apoptosis (natural cell death) in cancer, therefore, you receive a combined effect.
You can see a comparison made by researchers that observed how well 1) Paclitaxel, 2) DCA and 3) Paclitaxel + DCA work on mice tumors below.
(In vivo growth of tumors in mice treated with DCA alone or in combination with paclitaxel.)
You can also find the study on DCA + Paclitaxel in the following link: Dichloroacetate restores drug sensitivity in paclitaxel-resistant cells by inducing citric acid accumulation.
Hope you find this information useful,
I have a question about DCA, next week I start with immune therapy because I have lung cancer. Is it safe and can I still use DCA?
Q: Dear Sir or Madam, I have a question about DCA, next week I start with immune therapy because I have lung cancer. Is it safe and can I still use DCA? Best regards, Alfredo.
A: Dear Alfredo, thank you for your letter. We are getting similar questions often, therefore, we will try to explain DCA and immunotherapy in greater detail.
In most cases, using Sodium dichloroacetate with checkpoint inhibitors such as pembrolizumab (Keytruda), atezolizumab (Tecentriq) and other similar drugs is a great option. It does not look that DCA could be unsafe with any type of immunotherapies. (Ref.)
Immunotherapy helps the person’s own immune system fight against tumors. This class of medications is especially useful when the cancer develops resistance against conventional chemotherapy treatment. It also allows the immunity to bypass the special proteins that cancer cells develop as “camouflage” to continue growing and expanding.
As the cancer progresses, it continues to develop an acidic environment around it. Lactic acid is considered an important factor in driving cell invasion, angiogenesis and immune suppression.
Unfortunately, this process disables the immune system from fully engaging in tumor eradication. Furthermore, it diminishes the effectiveness of immunotherapy. The mechanism can be seen in the scheme below. (Ref.)
It is proven that DCA successfully inhibits aerobic glycolysis in cancer. This decreases the massive amount of lactate secreted by the tumor cells and prevents acidosis. The surrounding extracellular space remains in normal pH, thus the immune system can recognize and destroy tumors more effectively.
Considering everything, if you aim to efficiently treat cancer, Sodium dichloroacetate and immunotherapy can go hand in hand.
These are the key points that you should keep in mind when using DCA alongside immunotherapy:
• You should be free from peripheral neuropathy caused by previous chemotherapy treatment,
• If you develop rare neurological complications from immunotherapy such as Guillan-Barre syndrome, encephalitis or any type of neuropathies, please stop DCA treatment until the side effects resolve,
• Avoid using DCA, Vitamin B1 and Alpha-lipoic acid during your stay at the hospital while you’re receiving immunotherapy, you can resume DCA and supplements 2 days after you’re released from the healthcare setting,
• If you’re receiving cytotoxic chemotherapy, such as platinum based compounds (cisplatin, carboplatin, oxaliplatin) or taxanes (paclitaxel, docetaxel) – avoid using DCA and Alpha-lipoic acid 3 days before hospitalisation and 7 days after receiving chemotherapy infusions. After that time period, if you haven’t developed chemotherapy induced peripheral neuropathy, you can continue using the DCA protocol as usual.
Remember, DCA fights cancer on its own and can be used as monotherapy, but when it is incorporated with immunotherapy, the combination should work even stronger. (Ref.)
Hope you find this information useful.
My Aunt has stage 4 colon cancer with metastasis. Do you recommend starting DCA treatment and if so what dose should she take?
Q: Good Day, my Aunt has stage 4 colon cancer with metastasis. She is 5’7 and is weighing 140 pounds. Do you recommend starting DCA treatment and if so what dose should she take? Thank you. Isabel.
A: Dear Isabel,
thank you for your question. DCA therapy can help in almost every case of cancer, with varying degrees of success. The majority of people experience improvement in their symptoms, some have their disease stabilized and live without further cancer progression, and some even achieve remission thus remaining cancer-free. Nevertheless, stage IV colon cancer means that the tumors have spread in the body, this could make the treatment more difficult.
Despite that, a clinical case published by Dr. A. Khan displays that DCA can be great for treating advanced colon cancer even when traditional medical treatments fail. You can read the study here: Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy.
In the example of this 57-year-old woman, the stage IV colon cancer was stabilized with the help of Sodium dichloroacetate therapy and did not progress. It also did not cause any serious toxicity in the period of 4 years. The female remained highly functional and could continue running her own business, which proves that DCA treatment can be less debilitating than traditional chemotherapy.
We could go on and on about the potential benefits of the Sodium dichloroacetate. To answer your question, we would recommend your aunt trying DCA. She can take it as a single treatment or combine it with the traditional chemotherapy (5-fluorouracil, oxaliplatin or irinotecan etc.) or immunotherapy (Avastin/bevacizumab).
You can take DCA with Avastin without taking any breaks. However, when you‘re receiving chemotherapy – please make a two day break from DCA and Alpha-lipoic acid before getting chemotherapy and a three day break after receiving chemotherapy. Afterwards you can resume to taking the DCA protocol as usual.
For your aunt, weighing 140 lbs, she should begin with 12,5 mg / kg a day. Take it for two weeks then do a one week break. This would mean that she takes one of the following:
1) 800 mg of DCA powder, 2) two 333 mg capsules with breakfast and one 333 mg capsule with dinner, 3) one 500 mg capsule with breakfast and one 500 mg capsule with dinner. If she tolerates DCA without any problems, she can move up to taking 25 mg / kg a day. Take it for two weeks, then take a week off. Repeat the cycles. Take one of the following:
1) 1600 mg of DCA powder, 2) three 333 mg capsules with breakfast and two 333 mg capsules with dinner, 3) two 500 mg capsules with breakfast and one 500 mg capsule with dinner. Don‘t forget to take the advice and supplements we describe here. Don’t forget to take Vitamin B1 and Alpha-Lipoic acid with DCA just like we described. From our experience, we can tell that this is the biggest mistake some people tend to make. Here is an article on that: https://www.dcaguide.org/methods-and-supplements-for-preventing-dca-side-effects.
I am wanting to use DCA with my cats as well, one who is being tested for possible lymphoma. Do you have any recommended dosages for pets/animals, or can I just use the dosage calculator and plug in their weight (10-15 lbs.)?
Q: I am wanting to use DCA with my cats as well, one who is being tested for possible lymphoma. Do you have any recommended dosages for pets/animals, or can I just use the dosage calculator and plug in their weight (10-15 lbs.)? Thank you so much for your website. It is greatly appreciated. Jason B.
A: Dear Jason,
thank you for your kind words. Unfortunately, we do not have a lot of information on scientific literature, which discusses cancer treatment in cats. We would recommend you to not exceed 10 mg/kg of DCA.
Start by giving your pet half of the recommended dose (5 mg/kg). If she tolerates the medication without any visible side effects, increase the dose to 10 mg/kg after 21 days. The schedule should be 14 days on, 7 days off (for flushing out the excess DCA). Once done, repeat the cycle.
Your best bet would be to order it from Amazon or to check our listed suppliers.
DCA at Amazon: https://www.amazon.com/s?k=dca&ref=nb_sb_noss
These DCA suppliers ship to Canada without bigger problems: DCA-LAB Sigma-Aldrich Pharma DCA
My sister has advanced hormone receptive breast cancer with extensive liver mets. We’d like to try DCA, my only concern is as her liver isn’t in a great way is it safe to take? My worry is liver failure. Unfortunately, we can’t get it via IV in the UK.
Q: My sister has advanced hormone receptive breast cancer with extensive liver mets. We’d like to try DCA, my only concern is as her liver isn’t in a great way is it safe to take? My worry is liver failure. Unfortunately, we can’t get it via IV in the UK. I’d be greateful for any information. Kind regards, Reena T.
A: Hello, Reena!
Is your sister on Tamoxifen? (If yes, read this article – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312350/. Tamoxifen + DCA can have a synergistic effect)
From our narrow knowledge, we haven’t encountered anyone who took DCA and experienced liver problems. However, I would approach this treatment option with relative caution and maybe try lower than medium doses due to existing liver damage.
There have been no deaths related to DCA usage and you can find all of the side effects in this article:
https://www.dcaguide.org/dca-safety-and-side-effects.This is what we’ve the article mentions regarding DCA and liver function:
▪ Mild liver enzyme (AST, ALT, GGT) elevation, without symptoms. A majority of medications can cause mild liver enzyme changes in the blood. DCA can cause minimal liver AST,ALT, GGT elevations (about 50 – 60 U/l) for 1 % of the patients. These little alterations should not cause any worries. A more acute and bigger liver enzyme increase can be caused by antibiotics, Tyenol/Paracetamol (acetaminophen), certain types of medicinal herbs and birth control pills. (Ref.)
▪ DCA and the liver. In case of liver failure and severe jaundice don’t use high doses of DCA, because Sodium dichloroacetate is metabolised in the liver. In situations like these, DCA should be administered intravenously and not through the mouth. If the patient experiences AST and ALT or bilirubin elevation by 150% from the upper reference norm, a pause should be made (Ref.)”
If I was in your situation, I would check her liver function with liver enzyme blood test. I wouldn’t take DCA if AST or ALT were higher than 100 U/l. Elevated Bilirubin can also be a red flag in this situation. All in all, she could use the oral form DCA orally, just in lower quantities, such as 10 – 20 mg/kg DCA daily.
I/V DCA injections are difficult to find in the UK and are mostly given in Canada and Germany.
We hope we shed some light on your question.
Hi, I was just wondering if DCA can help with MS at all?
Q: Hi, I was just wondering if DCA can help with MS at all? Thanks Claire
A: Hello, Claire.
Unfortunately, there have been no significant studies regarding DCA usage for Multiple sclerosis.
We also can’t confirm that DCA mechanism could revert the damage MS does to the nerves.
As far as our limited knowledge enables us comment on the subject, your best bet would be to use glatiramer acetate + B – interferon (this is a classical choice). The following years were interesting on many disease therapies, as the biological therapy agents have shed light on many disease treatments. Fingolimod (Gilenya) and Dimethyl fumarate seem to be promising new agents that can slow down the progression of Multiple sclerosis.
Campath, Rituximab and Ocrelizumab are promising new approaches towards MS.
Consult your doctor on the subject. A neurologist would be your best bet. From our personal experience, we have seen people who have regained their ability to walk and live a better life with the help of specific rehabilitation procedures for MS.
My Dr. Gave me DCA capsules… 333 mg capsules to take 2-2x a day… I tried to take them, would get sick & throw up immediately… do you have any idea why this would be happening?
Q: My Dr. Gave me DCA capsules… 333 mg capsules to take 2-2x a day… I tried to take them, would get sick & throw up immediately… do you have any idea why this would be happening? Thank you…Sincerely. Troy B.
A: Hello, Troy.
The situation is rather strange. It could be due to the fact that your doctor was prescribing you with impure DCA.
DCA can irritate the stomach mucosa. However, we’ve got the subject covered in our article:
“On rare occasions, Sodium dichloroacetate administration can result in heartburn or nausea. If this is the case, try taking DCA after you eat a little bit of food and drink some fluids to avoid taking the medication on an empty stomach.
If that didn’t resolve the problem, you should try taking medications that lower gastric acid secretion – Proton pump inhibitors. Any type of PPI is acceptable provided the fact that they don’t have any major differences.
▪ Pantoprazole / Omeprazole / Esomeprazole
(take one 40mg tablet per day, at the same time. Take it at least 30 minutes before your meal and DCA.)
For convenience purposes, we recommend using Pantoprazole because it doesn’t seem to have any poor interactions with other medications. However, any other Proton pump inhibitors should have the same effect.
Let us know if you have any more questions.
Can we use along with Keytruda/Pembrolizumab ?
Q: Can we use along with Keytruda/Pembrolizumab ? Jon D.
A: Hello, Jon.
Yes, DCA can be safely used with Keytruda (Pembrolizumab) as no drug-drug interactions are expected. (Ref.)
As far as we heard from our own experience, there haven’t been any bad interactions between Sodium dichloroacetate and biological therapy.
Also, based on research and cancer biology facts, it seems that DCA and immunotherapy can go hand in hand. (Ref.)
You can find more details in the previous answer that analyses Sodium dichloroacetate and immunotherapy in-depth. (32)
I would like to purchase from DCA Lab as it is quite a good price compared to others, however I want to make sure that it is ok for human consumption?
Q: Hello, I would like to purchase from DCA Lab as it is quite a good price compared to others. However I want to make sure that it is ok for human consumption. I heard some places use toluene or other chemicals to purify which is of course dangerous to humans and I just want to make sure that even though they are cheaper it can be used for humans and if you guys have experience with this company and others using their products. Thank you, Farzad
A: Hello, Farzad.
DCA is mostly sold as a lab chemical worldwide, because it is currently not registered as a drug or a food supplement. However, this could happen any time soon. It is considered as an alternative cancer treatment in Canada for example. You can read more in this document: http://www.oicc.ca/uploads/dca-health-professional.pdf.
Regarding your question about DCA Lab, we have never asked them if they use toluene or other harmful chemicals. Nevertheless, we do believe that they have developed a safe technology, which enables them to synthesize great quality material. Their products are used in clinical trials with patients, therefore, it‘s safe to assume that they are legitimate.
We know dozens of people who are taking their Sodium dichloroacetate and we have never heard that anyone experienced any complaints related to harmful chemicals in their products.
Please also check this analysis we have made about the available DCA products to get a better idea on the global situation: https://www.dcaguide.org/dca-quality-analysis.
In the analysis, look at the anion and gas chromatography tests. They confirm that no toluene has been detected in DCA Lab products. Every DCA seller should provide a certificate of analysis, which proves the purity of their product. DCA Lab is one of suppliers that provide CoA‘s with their production.
Sigma-Aldrich and Tocris also produce exceptional quality Sodium dichloroacetate. Please consider them also. Avoid buying Sodium dichloroacetate that could have large quantities of impurities as these could be toxic if used for a longer period of time.
Can you take DCA with high dose IV Vitamin C treatments?
Q: Can you take this with high dose IV Vitamin C treatments? Daniel
A: Hello, Daniel.
We have followed hundreds of cases where people take DCA to treat their tumors and we noticed that a lot of people take Vitamin C additionally to their anti-cancer regimen.
You should avoid self-medicating with high doses of Vitamin C perorally, because it will not enable you to achieve the concentrations needed to have any effect. The only way to do this correctly, is to have someone give you Vitamin C through intravenous injections.
However, please be cautious. There are dangers. The biggest concerning side effect of high dose Vitamin C is oxalate crystal formation in the kidneys. This can happen after frequent Vitamin C administration in large quantities.
We have found these rare cases in medical journals. One man has been taking huge doses of Vitamin C for a couple of years orally for thyroid cancer relapse prevention and after 2 years he experienced kidney damage due to oxalate crystal formation as a side product from Vitamin C. You should keep this risk in mind and stay alert.
Regarding your question about DCA and high dose IV Vitamin C – we haven’t heard any interactions and we firmly believe that this shouldn’t cause a problem. Both treatments should be well tolerated and have no interactions with one another.
Hello. So is dcalab.com selling verified high purity DCA by an independent lab? Is it safe to take?
Q: Hello. So is dcalab.com selling verified high purity DCA by an independent lab? Is it safe to take? Thanks. Dan
A: Hello, Dan.
As far as we know, their DCA is of high quality. Over >99% pure. Their product has also been used in a couple of clinical trials with patients: 1) A pilot study done by Prof. F. Comhaire in Belgium on treating myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) with Sodium dichloroacetate (link), 2) A phase II clinical trial done by the University of Edinburgh using DCA as a possible treatment for endometriosis-associated pain (link).
There is a quality comparison analysis on our site where we compare the most popular DCA suppliers. You can find a detailed quality analysis of each brand. The method of anionic and gas chromatography was used to get the results: https://www.dcaguide.org/dca-quality-analysis.
We gave the maximum rating to two suppliers:
-DCA Lab (they’re an independent laboratory that specializes solely on high quality synthesis of Sodium dichloroacetate),
-Sigma-Aldrich (they’re a big company in Germany who manufactures a lot of chemical compounds. Their DCA is also of high quality. However, it is often hard to place an order).
DCA LAB is also listed on www.molbase.com, which states that their product is 99.9% pure.
Based on this information, we believe that DCALab.com offers high purity Sodium Dichloroacetate that is verified. They also have great customer support.
Nevertheless, DCA is safe to take in most of the cases. On the other hand, 95-97% pure DCA can have synthesis byproducts such as Sodium monochloroacetate, which can be toxic. Therefore, we advise you to choose a verified supplier and to avoid online shops like https://www.alibaba.com/ for your own safety.
Should we continue and disregard once a day diarrhea? We are taking it low as far as the dosage calculator is concerned.
Q: Hi, we have purchased DCA and from the first day there was diarrhea this is the second day so it‘s two days once a day, should we consider the dose of capsules 333 a high dosage? This man has had tumor on his vocal cords, which were removed as well as a part of his larynx . So now he was advised to follow chemo, which he won’t cause doctors said his tests revealed that something wasn‘t right, probably spread after surgery. Should we continue and disregard
once a day diarrhea? We are taking it low as far as the dosage calculator is concerned. Thank you in advance. Victoria
A: Hello, Victoria.
This is the first time we’ve heard that someone would develop diarrhea after taking DCA. Diarrhea is not a documented side effect of Sodium dichloroacetate. In extremely rare cases, diarrhea could be a result of an allergic reaction. However, symptoms like itchiness, hives, shortness of breath, cough, swollen face should also be present. On top of that, allergic reactions to DCA are extremely rare. Personally, we have never encountered them.
We have followed hundreds cases of people who are taking DCA, yet we have never observed that Sodium dichloroacetate would cause loose stools. It is most likely caused by other reasons and should be investigated by his doctor. DCA dose size should not impact the intensity of diarrhea, therefore, he can take more than just one 333 mg capsule.
On the other hand, one of the things that some people experience in their digestive system while on DCA is stomach irritation. Sodium dichloroacetate powder is a little bit acidic, however, most manufacturers use buffers in their product to make it neutral. Using capsules or taking DCA with/after food also quickly fixes this problem.
Maybe it’s just bad food, too much coffee, too much spices, stress or his overall condition ? Did the man have any kind of chemotherapy lately ? Oncological drugs often cause loose stools. We would advise you to take a short break (about 3 days) from taking DCA and then start again. Observe if the diarrhea returns.
He should also take plenty of clear fluids, at least 8 glasses of water or tea. Eating frequently in small amounts of low fiber food should also help. For example, bananas, rice, noodles, white bread, skinned chicken or turkey, fish.
If all of this fails, try taking Imodium (Loperamide). Start with 4 mg initially and afterwards give him 2 mg after each loose bowel movement.
Hope this helps.
Could you kindly specify what blood tests should be done and frequency of testing once the treatment has begun?
Q: Could you kindly specify what blood tests should be done and frequency of testing once the treatment has begun. I have been doing the CEA every 3 months, which is on a continual rise. My Dr knows nothing about DCA, but is willing to work with me if she is aware of what should be checked regularly. Keith
A: Dear Keith,
thank you for your question. In short, you should monitor your complete blood count, your liver enzyme levels (AST, ALT, GGT), bilirubin, CRP (C reactive protein), creatinine, urea, electrolyte levels and CEA.
•Liver enzymes are important to monitor your liver function. Rarely, but they can get elevated from the DCA and the other natural treatments that you‘re getting. They can also rise if you take too much paracetamol/acetaminophen (Tylenol), antibiotics or other drugs that can cause a liver reaction. Cytotoxic chemotherapy can as well cause liver injury and the elevation of liver enzymes as well as bilirubin.
Stop taking DCA if you experience abnormal liver enzyme (AST, ALT, GGT) elevation 2.5 times from the upper limit of normal levels. Take 1) silymarin or milk thistle, 2) essential phospholipids. Take a break till the liver enzymes return to normal levels. Then you can resume DCA.
•CEA is a tumor marker that is most useful for tracking the dynamics of cancer. The increase of CEA might indicate that the tumor is growing while the decrease of CEA might indicate that the tumor is decreasing in size. Have a regular check every 3 months to see whether the cancer is responding to therapy, also check if stabilisation is achieved.
This is how your papers should look like.
• Full blood exam / Complete blood count. It is a basic blood test that should be done in every hospital or clinic setting. 1) Reduced HGB (hemoglobin) could mean that you have iron deficiency anemia, other types of anemia or chronic bleeding. 2) Reduced WBC (white blood cells) and neutrophils are often encountered 1-3 weeks after cytotoxic chemotherapy and could indicate suppressed bone marrow function. This could lead to increased susceptibility to infections as well as fever. 3) Low platelet count (below <30) could indicate that you‘re more prone to bleeding after medical procedures or when you hurt yourself. An example of a complete blood test would be:
• Basic metabolic panel. It shows the blood biochemical properties which are important to monitor the function of the kidneys, liver and other organs. 1) Glucose shows whether you have diabetes, chronic catabolism, 2) Creatinine tells a lot about your kidney function. Usually elevation above the normal level indicates decreased kidney function, dehydratation, 3) Urea also indicates your kidney function as well as catabolism intensity in the body as it‘s a byproduct of protein breakdown, 4) Calcium levels can be elevated if there are endocrine disorders present, it‘s also frequently elevated when one has cancer (especially lung cancer), 5) Albumin and protein levels are important to monitor if you‘re suffering from cachexia, in case they‘re down please consider adding more protein to your diet or additional protein supplements, 6) Sodium, potassium and chloride are important because they maintain your blood-pressure, they participate in the generation of nerve impulses. Levels below or above the norm can be dangerous in some cases. Potassium significant drops or elevation can cause heart rhythm problems. 7) Alkaline phosphatase can get elevated in case of obstruction in the bile or if metastasis are causing bone breakdown. 8) LDH is most often elevated in cases of leukemia, it signalizes that there is blood cell breakdown going on. 9) AST, ALT and GGT enzymes are important to monitor your liver enzymes.
An example of a comprehensive metabolic panel would be:
• Tumor markers. These biomarkers are helpful in following the effectiveness of the therapy. Their elevated or reduced levels can help you follow the changes of your cancer. The most accurate tumor markers that correlate with the size of the tumor are – 1) CA-125 (for ovarian cancer), 2) PSA (for prostate cancer) and 3) CEA (for colon cancer). You can repeat them every 3 months to see how well is the cancer responding to treatment.
If possible, perform these blood tests at least every 1 or 2 months or before any major procedures to track your situation and discuss further steps with your oncologist.
Also, when you‘re following an anticancer regimen, it is helpful to have a Computed tomography (CT scan) or a Magnetic resonance imaging scan (MRI scan) at least once in 3 months. Ultrasonography (ultrasound) diagnostics can also provide information. CT scans are most valuable for tracking the majority of the cancers such as lung cancer, liver cancer, colon cancer, cancer which as spread and others. MRI scan is valuable for tracking
These imaging tests should provide information whether the tumor is growing or shrinking.
These tests are really helpful to build a complete image about your health as well as the changes in the tumor. Your doctor should be completely aware of these tests and explain you the importance of them in greater detail.
Regarding using DCA, is there any side effect concerning kidneys, would it result in kidney failure, what dosage should we use as he is at the last stage?
Q: Dear Sir /Madam, My father is stage 4 cancer, he has a mass of 6cm in the stomach, metastases 6-7 masses in liver, and some other parts. we were told that it was too late for chemothreapy and / or for operation. So while we are searching for alternatives, we found out DCA and wanted to try as our last chance. He is given very little short time. we already ordered the drug and would like to start using it as soon as possible but we have one important question: our father has aproblem with his kidneys as they are half functioning, this is one of the key reasons they would not apply chemothreapy to him since it can result to kidney failure on top of the cancer and spend his last days going to dialysis, so regarding using DCA is there any side effect concerning kidneys, would it result in kidney failure, what dosage should we use as he is at the last stage? Kurtulus.
A: Dear Kurtulus,
thank you for your question. We can confirm that DCA is safe to use with kidney failure. The main metabolism occurs in the liver and 99% of the drug metabolites are excreted through feces. We know patients that had severe chronic kidney disease and creatinine levels of 300-400 μmol/l (3.39-4.52 mg/dL) and have taken DCA without any problems.
Regarding the question about renal toxicity. We haven’t found scientific evidence that DCA could damage the kidneys:
”The drug does not alter renal concentrating ability or amino acid excretion. It slightly increases urinary lactate and pyruvate excretion, probably by inhibiting the specific tubular reabsorption of these anions.
Of note, in the phase Ib clinical trial for GBM, the researchers have observed no other toxicity from DCA, including abnormalities in cardiac function, renal function, or liver tests.”
This means that there is no available evidence of Sodium dichloroacetate damaging the kidneys. In fact, there is one in vivo research which states that DCA pretreatment could even help protect the renal function from some chemotherapy toxicity when used in together (Dichloroacetate Prevents Cisplatin-Induced Nephrotoxicity without Compromising Cisplatin Anticancer Properties).
*Important! This doesn’t apply if the patient has Polycystic kidney disease. One should avoid DCA when suffering from this condition as DCA could in theory aggravate the condition.
Regarding the question about dosing in such a situation. Your best option would be:
•take 50 mg/kg I/V DCA injections. If intravenous DCA is not available, then take Sodium dichloroacetate by mouth,
•take 12,5 mg/kg DCA powder for 14 days, make a 7 day break. If the patient tolerates the medication well without side effects, you can continue slowly try increasing the dosage to 20 mg/kg and 25 mg/kg after a while.
Don’t forget to take breaks (administrate DCA on 14 days on, 7 days off schedule), neuroprotective supplements and don’t forget that DCA shouldn’t be if severe liver failure is present.
How long term can a person take the DCA, 6 months, years ?
Q: Taking DCA 2 week on with 1 week off I understand… How long term can a person take the DCA, 6 months, years ? Kreuzman.
A: Dear Mr. Kreuzman,
thank you for your question. There are no official guidelines on how long DCA can be taken. Regarding safety, there have been documented reports of people taking DCA for more than 4 years (https://www.dcaguide.org/news/dca-and-cancer-melanoma-long-time-remission-and-stabilisation-case-presentation-101258). In some clinical studies, children have taken DCA for even longer periods of time. If someone has stage IV cancer which has spread, then DCA and other regimens should be taken as long as possible to keep cancer stabilized or cured.
How long can a person take Sodium dichloroacetate also heavily depends on how well the patient tolerates the DCA protocol, whether there is any preexisting liver failure or previous nerve injury. Diabetes can also cause nerve damage, therefore, preexisting diabetic neuropathy should be treated as much as possible before continuing the Sodium dichloroacetate treatment.
Some people take it for years to keep themselves in remission. Our suggestions for longer time periods would be:
• Stop taking DCA if you experience side effects. You can resume once they resolve.
• Stop taking DCA if you have severe chronic liver failure, acute hepatitis, chemotherapy-associated liver injury. You can resume DCA once the liver is in better function.
• Stop taking DCA if you experience abnormal liver enzyme (AST, ALT, GGT) elevation 2.5 times from the upper limit of normal levels. Take 1) silymarin or milk thistle, 2) essential phospholipids. Take a break till the liver enzymes return to normal levels.
• Take DCA till you treat cancer or you want to maintain remission.
Please don’t forget to take the neuroprotective supplements such as Vitamin B1, Alpha-Lipoic acid and, if possible, Acetyl-L-Carnitine.
I was interested in knowing if these studies are still being done in 2018 and if so how can one become a part of these studies?
Q: Hi, I was interested in knowing if these studies are still being done in 2018 and if so how can one become a part of these studies. Donyale
A: Hello, Donyale.
We are certain that a lot of studies related to DCA are still being continued till this day. However, clinical research that aims to try out DCA on people diagnosed with cancer is performed more rarely. Such studies require a lot of funding to sponsor the hospitals as well as doctors in order to participate in them.
Since Sodium dichloracetate is a generic drug and no pharmaceutical company can exclusively make profit from their investment in further research, it‘s a little bit harder to find new clinical trials that are searching for participants.
Nevertheless, there have been numerous clinical trials performed in the past. You can also find dozens of clinical cases that showcase successful DCA therapy on cancer patients. You can find these papers in our page: “DCA research”.
If you would like to participate in such studies, your best bet would be to contact an oncologist, which is familiar with Sodium dichloroacetate.
I wonder if any of the top rated DCA suppliers listed on your website can directly ship sodium DCA to mainland China?
Q: Hi, I wonder if any of the top rated DCA suppliers listed on your website can directly ship sodium DCA to mainland China. My aunt has been diagnosed with glioma three months ago, but her family refuses to use surgery or chemotherapy due to the concern over cost, lack of efficacy and severe side effects. She tried radiotherapy but the radiotherapy doesn’t work well. So we thought to give DCA a try. Much appreciated if you can help me with my request. Thank you. Dan
A: Hello, Dan.
Yes, we believe that most of the listed DCA suppliers should be able shipping directly to China. The top two suppliers get orders from all over the world, including India, South Korea, Japan and so on.
You can also try ordering it at Amazon: https://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Daps&field-keywords=dca.
We’re glad that you’ve found this alternative solution, because we‘re aware of the limited choices today for treating gliomas.
The most important clinical research on DCA for astrocytomas and glioblastomas discovered that Sodium dichloroacetate can be combined with all types of the possible treatments – surgery, radiotherapy and chemotherapy (in particular with Temozolomide).
DCA is perfect for treating brain tumors as it is small enough to cross the blood-brain barrier and is truly safe in comparison with other treatments.
Have you had proven positive results for AML (acute myeloid leukemia)?
Q: Have you had proven positive results for AML? Leah
A: Hello, Leah.
Yes, however, these people that had AML also took traditional chemotherapy. Acute myeloid leukemia is an aggressive cancer that needs to be closely monitored by doctors, because it can cause anemia (which makes you weak), trombocytopenia (which makes you prone to bleeding) and, most importantly, it causes an impaired immune response (which makes you prone to catching infections).
Therefore, we strongly advise every sufferer of acute myeloid leukemia to be monitored by their hematologist.
Theoretically, DCA should be beneficial for every type of cancer. In some cases, drugs such as DCA can help you maintain a longer remission. Some medications like fenbendazole can mix pretty well with Sodium dichloroacetate in order to maintain a cancer-free time period.
Sometimes, DCA can be the missing puzzle in the previous treatments that can finally help someone with AML achieve a lasting remission. The study explains instances like this in more detail: Perturbation of cellular oxidative state induced by dichloroacetate and arsenic trioxide for treatment of acute myeloid leukemia. Patients that cannot receive cytotoxic chemotherapy or have relapsed from remission could indeed benefit from the treatment of DCA.
Blood cancers are a difficult subject, however, we hope that our answer sheds more light on your journey.
Please don’t hesitate to ask us more in case you have more questions.
How do I know how many ml to take each day ?
Q: I mixed 1 (100 gram) bottle with 4 and1/4 cups of water. Now I have a 265 lb male which is x 9.09=2417.mg per day. The sry get only has ml or tsp how do I know how may ml to take each day. Kordy
A: Hello, Kordy.
Please read our article https://www.dcaguide.org/dca-dosage-and-usage-long-guide
carefully. Look at “The usage of DCA powder and capsules”.
You should mix a 100 g of DCA powder with 980 ml of water.
Then you get a solution in which 1 ml has 100 mg of DCA. If your dosage is 2400 mg per day, take 24 mililitres of the solution.
Here‘s a detailed video on how to do it:
How do I store DCA, we are in Texas. Is it adversely affected by exposure to air (the powder) ?
Q: How do I store DCA, we are in Texas. Is it adversely affected by exposure to air (the powder) ? Thank you. John K.
A: Hello, John.
Thank you for your question. The best conditions in which you can keep your DCA bottle or DCA solution once the container is opened should be away from direct sunlight and at cool temperatures (between 4 °C/39°F and 8 °C/46°F).
At home, the best place to store your DCA solution would be the fridge. You can also store DCA powder or capsules in a dark cabinet at room temperature (between 20 °C/68°F and 22 °C/72°F).
Any DCA product that you keep should be sealed shut as the powder and capsules tend to gather moisture over time which could ruin the product.
If your DCA powder or capsule bottle contains a silica gel packet – keep it inside as it will absorb humidity and protect the quality of your DCA.
The room air can be bad for your DCA, so we advise you to protect the powder from prolonged exposure to oxygen. If possible, keep the bottle closed when you’re not using it.
We hope this answers your question.
Question about dca what is better caps or powder?
Q: Question about dca what is better caps or powder thanks, John
A: Hey, John.
What you prefer – capsules or powder is entirely up to you. We will explain the main things you should consider when deciding what to use:
·Capsules are easier to take. You do not have to make a solution (measure the powder and mix it with room temperature water) to take your DCA. This makes it easier for you to take DCA everywhere you go in the morning or in the evening. You just need to have a bottle with DCA capsules and some water to help swallowing it down.
·Capsules usually are in 333 or 500 mg doses. This means that you can’t accurately take your dose if you’re trying to be precise. For example: if you weight 72 kg / 158.7 pounds and you’re trying to consume 25mg / kg daily (which would be 1800 mg in total), you will have to take more DCA to fulfill your daily needs. You’ll need six 333 mg capsules (1 998 mg) or four 500 mg capsules (2000 mg) to reach your daily goal. This means you will be forced to take ~200 mg DCA more every day.
We hope you get the idea.
·Powder form is cheaper and you can measure precise doses you wish to consume. You can use any quantity of DCA you like as long as you have a digital scale and know how to use it.
·The Powder form, on the other hand, requires more time as well as effort to be measured and dissolved in water before taking it. For this goal you need a digital scale and basic skills how to accurately measure powder.
If you’re busy and you can’t do this task every morning and evening – it can be a little bit problematic.
·You can always dissolve powder in a bottle or any other container and use a syringe to drink a pre-made solution. This is as easy as taking capsules, it also is the choice we recommend.
For example – dissolve 50 g of DCA powder in a 500 ml water bottle. You’ll get 100 mg for every 1 ml. If you need to take 900 mg in the morning, just take the 9 ml of the solution you’ve made and you will have your morning dose.
Here‘s a detailed video on how to do it:
Where is this drug made? Where can I get some?
Q: Where is this drug made? Where can I get some? Thank you, Maureen R.
A: Hello, Maureen.
The drug is made in various places. Some manufacture it in China and other suppliers resell it, some produce it in Europe, some of the DCA is made in North America.
The quality of each product differs, we recommend you checking all of the available suppliers below:
These are the quality analysis we have done:
If you have some understanding of chemistry, you can check out the chemical analysis of each different brand DCA.
Anion chromatography charts of every available product:
DCA-LAB Sigma-Aldrich Pure DCA Pharma DCA
There are some options available on Amazon.com, most of the products here are trustworthy:
Avoid buying Sodium dichloroacetate that has a higher impurity percentage as these impurities tend to be harmful and can cause new problems if used for prolonged periods of time. Clean, high-grade DCA can be used for years without any worries, provided that you follow the correct dosing rules and administration times.
What is the beginning daily dosage of DCA for a person weighing 220lbs ? How much Vitimin B1 and how often?
Q: What is the beginning daily dosage of DCA for a person weighing 220lbs? (BMI ideal weight 183-185bs)? How much Vitimin B1 and how often? Thank you, Charles.
A: Hello, Charles.
All of your answers are also answered in these pages: DCA dosage and usage (Long guide) and Methods and supplements for preventing DCA side effects . However, we will give you additional clarification on your specific situation.
For someone who is 220 lbs, first try out 15 mg/kg. This mean should start with 1500 mg daily. For the first cycle (two weeks on, one week off) take 1500 mg of DCA (750 mg after or with breakfast and 750 mg after or with dinner). Take this for two weeks and then stop taking DCA for one week.
Then, if you feel okay after the first cycle, move on to a larger dose: 25 mg / kg. Take DCA 1000 mg two times a day: 1000 mg with breakfast, 1000 mg with dinner.
Don‘t forget to take Vitamin B1 (thiamine) three times a day: 100 mg in the morning, then 100 mg with lunch and 100 mg at dinner. If you can get hold of benfotiamine (a better version of Vitamin B1), take it in the same fashion, but 150 mg in three divided doses.
It would be great if you could add Alpha-lipoic acid to your plan. Alpha-lipoic acid – take 300 mg with breakfast, 300 mg with lunch and 300 mg with dinner (total 900 mg daily). As with Vitamin B1, take it every day with no breaks.
Consider adding L-Carnitine to your DCA regimen.
Your total plan should look like:
1) DCA 1000 mg two times a day: 1000 mg with breakfast, 1000 mg with dinner. Take it daily for two full weeks, then take a break of one week. Repeat. 2) Vitamin B1 (Thiamine) – take 100 mg with breakfast, 100 mg with lunch and 100 mg with dinner. Benfotiamine is an even better form of Vit. B1 if you find it (then take 150 mg divided in three parts daily). Take every day, with no breaks. 3) Alpha-lipoic acid – take 300 mg with breakfast, 300 mg with lunch and 300 mg with dinner (total 900 mg daily). Take every day, with no breaks.
How long can I use DCA after the package has been opened? Does it go out of date quickly when it
is exposed to air? Do you suggest taking metformin together with DCA?
Q: Hi. How long can I use DCA after the package has been opened? Does it go out of date quickly when it
is exposed to air? Do you suggest taking metformin together with DCA? Thanks, Kristina.
A: Hello, dear Kristina.
You should try looking for the expiration date on the package of the product you purchased. Typically, if DCA doesn’t gather moisture inside, it can be kept for a few years. This is why we advise you to store it somewhere cool. Make sure that the bottle is tightly sealed at all times.
Also, the question regarding storage is answered with details in this article:
We have observed using metformin + DCA for some time now, it seems that the combination work quite well together. For example, look at this study: Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells. Nevertheless, don‘t overdo metformin (not more than 500 mg or 1000 mg daily if you don‘t have diabetes). Also, avoid metformin if you have kidney diseases.
If you can‘t tolerate metformin, you can try a natural alternative that has some of its benefits – berberine.
For stage 4 it recommends DCA to be taken constantly. Does this mean without breaks ? For how long ?
Q: For stage 4 it recommends DCA to be taken constantly. Does this mean without breaks? For how long? I’d guess until markers are normal and there is no need to continue. Or do you recommend continuing as a preventative? Please clarify. Thanks, Dana
A: Dear Dana,
it means that you still need to take breaks, otherwise peripheral neuropathy can ”kick-in” more swiftly and prevent you from using DCA for cancer prevention as soon as you‘re in remission. If one has stage IV cancer, the treatments that are given by the oncologist should also be continued.
Most of the time, it will be chemotherapy, target therapy or immunotherapy. DCA goes well with most of these treatments, however, it goes especially well with target therapy and immunotherapy. A lot of cancers develop some sort of resistance to chemotherapy after its given frequently.
Please understand that the main goal of treating stage IV cancer is transforming it into a chronic disease and prevent it from causing further harm through metastastis and growth. To achieve this, someone with stage IV cancer should constantly take some kind of anti-cancer treatment and monitor his health as well as tumors as a routine.
Therefore, take DCA as a single agent or in combination with other methods to prevent cancer from spreading and getting larger. This means taking it for the rest of your life. Sometimes you develop any side effects such as peripheral neuropathy, which will make you to take a pause until they resolve. After they‘re gone, resume the DCA protocol.
Cancer markers are one of the main ways to follow the progress / regress of the tumor advancement. The most accurate tumor markers that correlate with the size of the tumor are – 1) CA-125 (for ovarian cancer), 2) PSA (for prostate cancer) and 3) CEA (for colon cancer). You can repeat them every 3 months to see how well is the cancer responding to treatment.
If they drop, it means that the malignancy is shrinking. One must also have imaging scans performed, to see if tumors are decreasing or increasing in size and to make sure if all the metastasis are gone.
If you achieve remission, you can lower your DCA doses. DCA can be used as a preventative for cancer relapse if desired. Most of the cases take in doses lower than before, at least 50-80 % of the original dose that helped you achieve remission.
Don’t forget that you can combine DCA with other natural methods or regimens that prevent cancer.
I am looking for support with guiding my mother (who is diagnosed with uveal melanoma) with start of using DCA. However we can’t find any specialist/professional in our region. Can you help us out with this?
Q: Dear DCA guide, I am looking for support with guiding my mother (who is diagnosed with uveal melanoma, stage 3, mets) with start of using DCA. She already started ketogenic diet for some time, but now wants to add DCA with this. However we can’t find any specialist/professional in our region. Can you help us out with this? Regards, Cees.
A: Dear Cees,
we would like to show you a really interesting study about melanoma + DCA Long-term stabilization of metastatic melanoma with sodium dichloroacetate.
To make a long story short, a young man used DCA for a handful of years and it stabilized his melanoma, even shrunk the lymph node metastasis. He finally got better and afterwards added immunotherapy to the treatment. This was a great result, since the previous treatments prior to Sodium dichloroacetate had little to no effect.
Your mother can definitely take DCA with Ketogenic diet for the treatment of Melanoma. It can stabilize as well as treat this type of skin cancer. Also consider talking with your oncologist, maybe he can add immunotherapy or targeted therapy to the picture for even better results.
If you‘re clueless where to start with DCA, you can find a lot of information that you need to know about Sodium dichloroacate for free in our site. Please read it closely. Analysing DCA information is a must.
Also, we advise you following your doctors advise, especially if he’s offering biological therapy for melanoma. You can use the Ketogenic diet and DCA with the conventional treatment options.
Regarding your question about specialists and medical professionals in Europe. There are many specialists and naturopathic clinics in Germany who prescribe Sodium dichloroacetate for cancer. However, we have no contact with them. You will need to find them yourself.
If you have the funds and the time, you can try reaching out Dr. Akbar Khan in Canada. He’s one of the best DCA oncologists in the world. You can find his site here at Medicor Cancer.
Does anyone know if Kisqali (ribociclib) is compatible with DCA? Or even complimentary? Do you know of any clinics/practices in Australia competent in administering this drug?
Q: Hello, my dear wife has been struggling with breast cancer and this site has been a great ray of hope. She has recently been put on a drug called Kisqali (ribociclib). Does anyone know if it is compatible with DCA? Or even complimentary? Do you know of any clinics/practices in Australia competent in administering this drug? I look forward very much to hearing from you. Richard.
A: Hello, Richard.
Unfortunately, Ribociclib (Kisqali) is quite a new therapy against breast cancer and we have found no studies, which discuss of combining it with DCA. However, we’ve reviewed the pharmacodynamics and pharmacokinetics of Ribociclib and it doesn’t look like it should interact badly with Sodium dichloroacetate. In fact, as mentioned before, we have no bad experiences of combining DCA with targeted therapies.
Please read carefully our work at DCA Information and learn all you need before administering DCA to your wife. Everything should be fine. Just don’t overdose the DCA and remember that the protective supplements that we recommend with the DCA protocol are obligatory.
DCA + Kisqali shouldn’t cause any problems when used together. In fact, they could both provide benefits. Another therapy for breast cancer, Tamoxifen, has a synergistic effect with DCA.
If you want real professional help, please contact Dr. Akbar Khan. He has a cancer center in Canada. He’s one of the most famous oncologists who uses DCA with other conventional cancer treatments. We doubt that there is someone better in this field than him.
Where can I buy dca and thiamine in Europe?
Q: Where can I buy dca and thiamine in Europe? Elisabeth K.
A: Dear Elisabeth,
thank you for your question. You can order Sodium dichloroacetate in Europe from Amazon or directly from the manufacturers.
DCA in Amazon: https://www.amazon.co.uk/s?k=dichloroacetate (UK version).
DCA directly from the EU manufacturers: DCA-LAB Sigma-Aldrich Pharma DCA.
Thiamine should be found in every European city that has a pharmacy. You can easily find it at your local pharmacist, just ask for ‘‘Vitamin B1“.
Thiamine is a one of the most widely accessible supplements, should be available in any pharmacy or supplement shop and can also be purchased at Amazon: https://www.amazon.co.uk/s?k=Thiamine