How long has humanity been plagued by cancer? The answer might surprise you. It looks like our ancestors faced the same challenges as we do in the 21st century.

Some of the earliest proof of cancer is found among ancient mummies from Egypt. Archaeological evidence suggests that people of the past suffered from the same types of tumors as people do nowadays.

However, ancient Egyptians had no clear understanding what cancer is and hence no effective therapies existed. The cause and cure for the dreaded disease have always remained a mystery. (Ref.)

Fortunately, in the last century the progress in understanding oncological diseases has been tremendous. When anesthesia became available, surgeons rapidly developed operations that removed the entire tumor along with cancerous lymph nodes. (Ref.)

During World War II, compounds blocking critical chemical reactions for DNA replication emerged. Further development of such cytotoxic agents led to the advent of chemotherapy. Unfortunately, these drugs targeted normal cells as well as cancer cells, therefore, safer yet effective alternatives were still needed. (Ref.)

Before long, more sophisticated treatments such as immunotherapy and targeted therapy became available in oncology. The better understanding of cancer biology resulted in new age medicines. These medications could boost the immune system’s response to target malignant cells and hinder cancer growth, division as well as metastasis. (Ref.1), (Ref.2)

Interestingly, the whole exploration process led to unexpected discoveries. Significant metabolic shifts were acknowledged to be a characteristic of many cancer types. Coupled with the emerging wave of drug repurposing these findings opened the door for metabolic cancer treatment and soon Sodium dichloroacetate became the most prominent example of this strategy. (Ref.)

Cancer metabolism

In 1923, a German biochemist, medical doctor and Nobel Prize laureate, Otto Heinrich Warburg, made a ground-breaking discovery vital in understanding the energy metabolism of cancer cells. This identified phenomenon is now recognized as the hallmark of cancer and is called the Warburg effect.

Otto Warburg observed the cells of a rat tumor and noticed that their growth is powered by extreme amounts of glucose (sugar) without the increased use of oxygen. This made no sense since using oxygen for producing energy from nutrients is a significantly more efficient way. Over a hundred years ago such findings raised more questions than answers.

Now it’s known that the enormous glucose hunger and reduced intake of oxygen grant cancer cells a unique set of evolutionary advantages. (Ref.)

One of the ways how cancer cells benefit from the Warburg effect is by shifting to rapid biomass production. The increased glucose uptake provides the cancerous tissue more building components for making new genetic material and protein, ultimately leading to increased cancer proliferation and growth. (Ref.)

In addition, it is well known that normal mammal cells are constantly supplied with oxygen, otherwise they would die quickly. However, malignant cells act in a totally different way. As the tumors grow rapidly, they often outgrow their oxygen supply. Needing no oxygen to fuel its growth and thrive, the cancer does not suffocate.

Soon the tumor cells switches its metabolism to aerobic glycolysis. It begins producing and excreting excessive amounts of lactic acid outside the cells, eventually leading to increased acidity of the tumor microenvironment. (Ref.)

Acidic tumor microenvironment promotes further invasion and metastasis by breaking down the extracellular matrix between our cells. Once the acidity level is elevated, it also helps cancer development in avoiding our immune system, the natural defense mechanism against malignancies. This is one of the reasons why the effect of immunotherapy can often start diminishing when treating advanced cancer. (Ref.)

At the same time, the tumor cells utilizes less oxygen, the mitochondria inside the cells start generating less reactive oxygen species that serve an important role in preventing as well as removing cancerous cells. The cancer begins avoiding a mechanism known as apoptosis. (Ref.1) (Ref.2)

Apoptosis is a normal process that occurs in our organism as a convenient way to eliminate cells that should no longer be a part of the body. It’s a form of natural programmed cell death that prevents tumors from developing and expanding in the first place. As a consequence of avoiding apoptosis, the cancer cells become immortal. (Ref.1), (Ref.2)

These are the main metabolic advantages that enable the tumors to thrive. Notably, the evolution of tumor cells is a rather complex process, which makes it a difficult disease to treat. However, this is just one side of the coin. On the other hand, the Warburg effect can be exploited against the cancer itself.

In diagnostics, humanity used this cancer metabolism phenomenon for diagnostics. The positron emission tomography (PET) scan reveals the tissues and organs that have abnormal metabolic activity.

Since the cancer cells have the Warburg effect active, they absorb radioactive glucose a couple of hundred times faster than the surrounding normal tissue. As a result, the tumors light up in the images and can be conveniently traced in the whole body. (Ref.)

In treatment, the Warburg effect could be the “Achilles’ heel” of cancer that was ignored for almost a century, since virtually all of the past cancer therapeutics focused on a gene-centered approach. The compound Sodium dichloroacetate acts in a completely different manner and instead corrects the abnormal metabolism of the cancer cell.

How DCA treats cancer?

It disrupts the chemical reactions that tumors use for their rapid growth, starving cancerous cells of nutrients. Moreover, it restores the “bad” metabolism in cancer cells. DCA is an activator of damaged mitochondria.

As a consequence of stimulating the mitochondria, DCA increases the production of reactive oxygen species in the cell. These changes induce further cellular mechanisms that lead to apoptosis, which in other words is selective tumor cell death. This results in decreased proliferation of cancer cells, decreased tumor size, symptom alleviation and increased host survival. (Ref.)

DCA treatment transforms the most aggressive cancer cells to less aggressive ones. Since the Warburg effect is only present in malignant cells, healthy cells remain unaffected by Sodium dichloroacetate.

What positive improvements to expect?

DCA is great for stabilizing the tumors, which means that they cease to grow and expand. This also leads to improved well-being and reduced tumor markers of the patient.

People can expect to regain their appetite, strength and weight. DCA also treats the chronic pain that is often present as a complication of cancer development.

In addition, Sodium dichloroacetate is also an option for someone with brain tumors since it crosses the blood-brain barrier.

Dr. A. Khan explains the benefits of DCA in his excellent lecture.

How to use DCA for cancer?

DCA should be used as a single agent or in combination with other regimens until there is no evidence of disease (NED) in the cancer patients.

Even when the cancer is gone, it’s advisable to continue using DCA for cancer at least 5 years in lower doses and have prophylactic screening once every 3-6 months. If the cancer is away even after 5 years, DCA treatment can be used in low doses occasionally as a prophylaxis to ensure that the tumors don’t come back.

We will finish this page as soon as possible. In the meantime, please use our DCA dosage and usage (Quick guide) or DCA dosage and usage (Long guide).

Cancer cells and DCA-resistance. How to overcome this problem?

The Sodium dichloroacetate molecule enters the cancer cell through the SMCT1 (SLC5A8) transporters.

Unfortunately, as the tumor tissue becomes more malignant and develops more mutations, the expression of the SMCT1 transporter goes down. Subsequently, DCA has a harder time entering the cells to produce its maximum anticancer effect. (Ref.)

If one has experienced a dramatic improvement at the beginning of DCA cancer treatment and after some time the effect has been diminished, it could mean that the tumor has developed some drug resistance to DCA. Nevertheless, there could be a practical solution to this issue. (Ref.1), (Ref.2)

Diclofenac 25 or 50 mg tablets orally 1-2 times per day can lead to the re-expression of DCA transporters. It also serves as an anti-inflammatory drug and a pain killer, which could help oncological patients manage physical pain.

The problem with Diclofenac is that it also suppresses the gastric mucosal barrier, which might lead to the stomach acid causing heart burn or small erosions. In more severe cases, it can cause peptic ulcers and bleeding if used for prolonged periods of time.

The solution to this problem is the additional use of proton-pump inhibitors such as Omeprazole (Prisolec), Pantoprozole (Protonix), Lasonprazole (Prevacid) or Esomeprozole (Nexium) 20 mg once daily, 30 minutes before breakfast. These medications reduce stomach acid secretion and thus prevent the most common Diclofenac-associated side effects. (Ref.)

Furthermore, there is evidence to suggest that Omeprazole enhances the effect of DCA. (Ref.)

The protocol to overcoming DCA-resistance in tumors:

  1. Diclofenac 25 or 50 mg one tablet once or twice daily, at least 30 minutes before breakfast and/or dinner (total 25-100 mg per day). Five days a week, two days break. Resume.
  2. Omeprazole (ideally), or Pantoprozole, or Lasonprazole, or Esomeprozole 40 mg once per day, at least 30 minutes before breakfast, daily, without breaks.

Examples: A) 160 lb person with no cancer-associated pain and diminished response to DCA therapy should take Diclofenac 25 mg twice daily with Omeprazole 40 mg in the morning. B) 220 lb person with moderate cancer-associated pain and diminished response to DCA therapy should take Diclofenac 50 mg twice daily with Omeprazole 40 mg in the morning.

*Diclofenac should not be used if one has severely impaired kidney function, liver disease, history of erosions or ulcers in the upper gastrointestinal tract, bleeding due to clotting disorders or asthma.

*Omeprazole or other proton-pump inhibitors should be avoided if the individual has osteoporosis, a broken bone or systemic lupus.

Ibuprofen, ketoprofen, fenoprofen, naproxen, indometacin, resveratrol and quercetin are not recommended with the DCA cancer protocol, since they tend to worsen the transportation of the DCA molecule into the cancer cells through the deactivation of SMCT1 transporters. (Ref.1), (Ref.2)

The evidence suggests that taking vitamin E supplements could actually undermine the cancer-fighting effects of DCA. (Ref.)

This is because procaine, which is not recommended for use in restoring SMCT1, has poor bioavailability and can only theoretically work in cell laboratory cultures. (Ref.1), (Ref.2)

can dca cure cancer medication can dca cure cancer medication
dca against cancer dca against cancer
dca and cancer treatment clinical trials dca and cancer treatment clinical trials
dca cancer cure drug brain breast colon dca cancer cure drug brain breast colon
dca cancer protocol supplement prostate liver and ovarian dca cancer protocol supplement prostate liver and ovarian
dca cancer testimonials dca cancer testimonials
dca cancer testimonials dca cancer testimonials
dca cure for cancer dca cure for cancer
dca cures cancer dca cures cancer
dca drug for cancer treatment dca drug for cancer treatment
dichloroacetate and cancer metastasis dichloroacetate and cancer metastasis
dichloroacetic acid (dca) for cancer treatment dichloroacetic acid (dca) for cancer treatment
dichloroacetic acid cancer metformin dichloroacetic acid cancer metformin
dichloroacetic acid cancer treatment patients dichloroacetic acid cancer treatment patients
medication dca powder for cancer pancreatic prostate melanoma medication dca powder for cancer pancreatic prostate melanoma
sodium dichloroacetate cancer effective treatment sodium dichloroacetate cancer effective treatment
sodium dichloroacetate cancer research sodium dichloroacetate cancer research
sodium dichloroacetate cancer treatment canada sodium dichloroacetate cancer treatment canada
what is dca for cancer medicine what is dca for cancer medicine
dca cancer therapy dca cancer therapy
image-dca-for-cancer-treatment image-dca-for-cancer-treatment

This Post Has 23 Comments

  1. Dominick Wong

    Is there anyone here who has pancreatic cancer stage 4 , who decided to not do chemotherapy and only treating it with DCA? Would you mind sharing and tell me your protocol and how long have you been doing it.

    1. Tom

      Hi. I’m 64 years old, diagnosed w. Pancreatic cancer -(Advanced, local adenocarcinoma stage 3; 2.6cm tumor) a few months ago. Initially I was opposed to chemo & had hopes of getting into a clinical trial involving Immunotherapy. I didn’t find one I’m a candidate for & decided I’d do chemo. There have been holdups & delays getting a Pet scan & I’m on the fence about chemo after hearing about Neuropathy & other side effects. Been doing DCA protocol. Recent scans show that tumor has not grown. I feel pretty good- very little pain, ok appetite, weight loss has stopped, no jaundice, great energy.

  2. Patricia Bradley

    Does fenbendazole kill cancer stem cells? or just the mature cancer cells?

    1. Lois

      As far as I know fenbendazole doesn’t have the ability to kill cancer stem cells. But on the other hand it has been used to treat certain types of cancer, and mostly effective against mature cancer cells.

  3. Carolyn M.

    I had Stage 2 Breast Cancer and coming up on 5 years remission. Praying the same for all of you!

  4. Katherine Greer

    My father also did this protocol and he lived 43 months post diagnosis

  5. Ruben Long

    So many people and animals suffer from cancer each year and are told there is nothing more that can be done. To hear that there is hope out there using a combination of drugs not used by conventional Drs or vets is something we should be aware of and more research should be carried out especially as it could save lives and cost less than conventional treatments. It is something many of us may need in the future for ourselves or our pets. Thank you for this information and I hope it can save other lives in the future.

  6. Chester Sal

    I started taking DCA very early November. A recent scan showed some existing tumors doubling in size, some stable-ish and some fast growth in other tumors. I wish you all the very very best in your healing journeys!

  7. Pauline

    My husband was diagnosed 8/21 with non Hodgkin’s lymphoma after being cancer free for 5 years. He started taking the DCA protocol the next month and the lump on his neck disappeared within weeks.

  8. Jerry Chandler

    6 month CT Scan results today. My oncologist said, “completely normal”! God has kept me All Clear for 3 years 5 months! Prayers answered! Never quit never give up no matter what!

  9. Chelsea Jefferson

    Can you take DCA when you’re on chemotherapy? My friend has stage 2 breast cancer and just started chemo (she had the removal surgery 4 weeks ago) with three more months to go.

  10. Clara m

    I was diagnosed 4 years ago today with triple negative breast cancer! Have been NED since June 2022! All Glory goes to God!

  11. Martha Rios

    DCA cancer protocol worked for me. Metastatic 2 x 2 cm lung tumor and invaded lymph nodes totally gone on PET/CT scan after 17 weeks

  12. Gregg Cunn

    Great news! Praise God! My recent biopsy’s have shown that my pancreatic tumor is dead! They only found necrotic debris and non-viable tissue.

  13. Joanna Barker

    I thank God every day for another day! As a cancer survivor with little over one year in remission now and several years of testing and checkups to go. I can assure you I know the meaning of being thankful down to the level of every breath taken.

  14. Morris Davis

    Just wanted to give some hope to anyone fighting this battle or helping someone fight the battle. Just had my 3 month scan. I was diagnosed a year ago with stage 3 small cell lung cancer. I started DCA protocol right before brain radiation. My first scan after this I was NED! To be honest I was scared thinking the world would think I’m crazy. But my heart said I had nothing to lose. I’ve also never ever mentioned a word to my doctors about taking any vitamins or this protocol.

  15. Mark Brown

    Buying from Amazon and it helps!

  16. Phillip Bar

    During the entire protocol with the DCA do you have to take the normally recommended supplements to prevent getting neuropathy as if you were taking DCA alone?

  17. Martha E.

    I’ve been taking DCA regularly since my diagnosis. The research shows that it doesn’t work on all varieties of my cancer. I had a period of 3 months without chemo while I was doing surgeries and my cancer grew and spread despite the DCA. Now the chemo that has been working very well this past year has stopped working and the cancer is growing again despite my use of DCA. Is it safe to increase the dosage and if yes, how much? Currently I’ve been doing 20mg/Kg. I adjust as my weight minorly fluctuates.

    1. Nicholas Brooks

      You can go up. Best results have been seen with 25 – 30 mg/kg but this might be because most people (in that study) didnt tolerate higher doses.

  18. Sharon Jenkins

    My sisters stage 4 Pancreatic cancer stopped growing and even shrunk when she used DCA. Unfortunately my brother who had built a home made Rife machine to treat her suggested she stop using it. She called me about two weeks before she died and felt that stopping use of DCA. was a big mistake. There is a side effect to watch for tumor lysis syndrome because it kills the cancer so quickly. It did not feel toxic at all but there is a protocol to follow. You also need to research all of its proper use and how to reverse it if you experience complications.

  19. Carol R

    I am currently on it and it seems to be working!!!

  20. Andrew Ward

    Dca Lab is very reliable. I’ve ordered their dichloroacetate several times

Leave a Reply