It is sad to admit that one of the two biggest health problems in the world is cancer. While we are still struggling to find cures for this illness, breast cancer continues to be one of the leading causes of death among women.
We would like to present a short and interesting research on how coincidence prevented breast tumours in a region of Chile. Furthermore, how this information could be valuable for someone who is considering DCA and other alternative routes to cure cancer ? It looks like dichloroacetate can be more effective with the help of other substances.
Arsenic trioxide has been considered as an old medicine for a long period of time. Most notably, it had value to treat a variety of diseases in ancient Greek and in traditional Chinese medicine 2000 years ago. Nowadays, in the last century, it was reintroduced as a strikingly effective medication against a highly fatal oncological illness - Acute promyelocytic leukemia (APL) - and is continued to be used as one of the best choices for its treatment.
Other than that, recent studies present interesting conclusions. It appears that some of the driest places on earth in northern Chile had significantly lower breast cancer occurrence due to ATO exposed drinking water. Ironically, the regions which later on had arsenic removal plants installed had a non-coincidental return to normal breast cancer rates in a couple of decades.
These bizarre findings led to speculations. Could arsenic trioxide be a potent healing substance for breast cancer and maybe even other malignancies?
It happens to be true. More up-to-date studies revealed that ATO does reduce cancer cell division rates and numbers in vitro, as well as in experimental animal tumor models. Arsenic trioxide could be a material which hasn't yet demonstrated its full potential.
As we already know, Dichloroacetate can be used as a safe way to help heal malignancies. Despite the fact that using DCA for the treatment of cancer is a relatively new idea, the drug has been used for decades to give medical care for people who have congenital lactic acidosis. The substance has already been observed for some time and its side effects are quite minimal in comparison with other chemical cancer treatments.
At the moment, it is known that Dichloroacetate can have a beneficial effect on a variety of cancerous diseases.
Furthermore, it appears that the substance can stop breast tumour growth and even provide a selective cytotoxic effect on aggressive breast cancer cells. This means that DCA can shrink tumours, prevent the rise of acidity in the tissues, stop angiogenesis and keep malignant cancer cells from spreading to the body.
Most importantly, the medication can be combined with other anti-cancer substances. DCA sensitizes the cancer cells towards other cytotoxic agents and enhances the pro-apoptotic effects of other drugs.
With this in mind, we can combine Arsenic trioxide and Dichloroacetate to achieve more dramatic results on breast cancer treatment.
As the study shows, the combination of ATO and DCA slows down cancer growth and causes apoptosis of breast tumour cells while doing all of this is in clinically relevant concentrations. That’s why the mix lets us achieve effective results while reducing the side effects to a minimum.
Arsenic trioxide, dichloroacetate and their combination don’t cause cytotoxicity on normal cells, but all of the three are beneficial for treating breast cancer. Surpisingly, the combination of the two has a much larger impact on malignancies which proves us why the mix should be used simultaneously.
The conclusions of the study leave us enthusiastic and eager for more researches on breast cancer. So far, the results seem promising and show the potential of this unordinary drug combination.
Ultimately, only one thing is still certain. A proper lifestyle, a balanced diet and the positive attitude of an individual can do wonders for one‘s health. Humanity has so many treatment possibilities these days – surgical removal of tumours, radiotherapy, chemotherapy...
It goes without saying that we keep our fingers crossed for every new research which could help us uncover safer, cheaper and more effective therapeutic options on dreaded diseases such as cancer.
Stay tuned for more information on the subject.
Full study on the topic:
Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells