Q: I am suffering from prostate cancer stage 2 for 7 years. Started taking DCA 500mg 3 times a day for 6 weeks (at the end of the month). I will check my PSA on the 30th of August 2018. In case of a positive result, I want to continue the treatment for another 2 months. My supplier was Pharmacy DCA for quick delivery from UK. I am thinking of DCA -LAB for the next shipment. Can you advise me, please. Best regards, Roger. A: Dear Roger, unfortunately, prostate cancer affects a lot of men in the world. Gladly, there is plenty of research discussing the subject. Firstly, you need to monitor your cancer treatment progress. Figure out whether the therapy that you‘re receiving at the moment and the DCA protocol are working. Please check your PSA levels and find out if it is increasing or decreasing. Repeat your PSA test once every 3 to 6 months. A Computed tomography or Positron emission tomography (PET) imaging scans as well as intrarectal sonography could also be helpful in monitoring whether the treatment is working or not. If the tumor marker and the size of the tumors are stable or decreasing - continue what you‘re doing. If they are increasing - consider changing or adding something new to your regimen. Also, please follow your doctor‘s advise as a primary guide. He‘s a healthcare specialist and understands your situation the best. Regarding your question about the suppliers, we believe that DCA-Lab is a great brand that offers good customer service as well as delivery times. You can‘t go wrong by choosing them. Nevertheless, consider reading our detailed review on the most popular Sodium dichloroacetate suppliers: https://www.dcaguide.org/suppliers/dca-lab. Fighting prostate cancer is a daunting task at first. However, you’ll quickly develop the habit of taking your personalized routine daily and finding out which options work the best for you. Another great addition to the DCA protocol is fenbendazole. Studies revealed that they both work complementary of each other. (Ref.) We recommend adding fenbendazole to your protocol for even better results. It‘s a great combination with DCA, especially for prostate cancer. You can find out more information about this repurposed veterinarian drug for cancer at https://www.fenbendazole.org/.
Q: I have an aunt with breast cancer IV. Can you inform me about the right products please? Daniel A: Dear Daniel, thank you for your email. We understand that this is a really hard time for you and your family. She should continue getting regular health exams by her oncologist as well as other doctors that are following her current situation. If your aunt is receiving any kind of therapy and it is not too heavy on her well-being, please continue doing that. The best results are achieved when you combine traditional and alternative medicine together. To answer your question, there are a number of available options for people with metastatic breast cancer. First of all, if she doesn't have peripheral neuropathy or liver function impairment, she can consider taking DCA (sodium dichloroacetate). You can find all the information you need on this page: https://www.dcaguide.org/dca-information. You can also choose where you get your product from all the suppliers that we reviewed: https://www.dcaguide.org/suppliers. You will definitely find something that can suit your needs. DCA needs at least 4-6 weeks to start working. Secondly, you could also use fenbendazole as a part of your anti-cancer protocol. There have been studies suggesting that DCA becomes even more potent when used in combination with fenbendazole: Fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. Fenbendazole also works against breast and a big variety of other cancers by itself. You can find more about fenbendazole on this site: https://www.fenbendazole.org/. Recently, we've heard reports that this medication can help people with breast cancer, stabilizing the disease or shrinking the breast tumors. Just please make sure that the relative doesn't have any significant liver problems such as cirrhosis or jaundice prior to starting fenbendazole. As with DCA, you also need some additional time for fenbendazole to start working. It is usually about 6-8 weeks. Last but not least, the third option that is quite similar to fenbendazole is niclosamide. It's a new substance that the complementary cancer treatment community has been following closely. However, it's still relatively young and needs more information on the exact mechanisms on tumors. Nevertheless, please give a look at https://www.niclosamide.org/ and research any available data on its potential against breast cancer. It should be great when used in combinations with other anti-cancer regimens. If she is currently receiving no angiogenesis inhibitors such as Bevacizumab (Avastin), your aunt can try Ammonium tetrathiomolybdate (TM). It is an anti-cooper agent that promotes survival in metastatic breast cancer. This molecule can be combined with DCA for better results. It should not be combined with chemotherapy. They had positive results in breast cancer patients in this clinical trial: Influencing the Tumor Microenvironment: A Phase II Study of Copper Depletion Using Tetrathiomolybdate in Patients with Breast Cancer at High Risk for Recurrence and in Preclinical Models of Lung Metastases. She should take 40 mg of TM three times per day with meals for about a week. Then…
Q: Is DCA successful in treating SCLC (small cell lung cancer)? Wayne A: Dear Wayne, thank you for your email. We have heard reports about people that successfully stopped SCLC (small cell lung cancer) progression with the help of DCA. One of them is in remission till this day and is still taking Sodium dichloroacetate for prophylaxis. However, as you have probably heard, SCLC is a really aggressive cancer and it needs the best measures to fight this disease. This means that DCA alone could still not be enough. If you haven't received a lot of nerve damaging chemotherapy and do not suffer from current peripheral neuropathy, you can consider trying DCA alone or alongside other cancer treatments. Just please don't stop your current health checkups by your doctor and follow his advice. A recent study has shown that DCA works well in combination with fenbendazole. (Ref.) There is also a growing community, which uses fenbendazole alongside conventional or alternative therapy to treat their cancer. Fenbendazole can sometimes do wonders when treating lung cancer. Give it a try. We advise you to try DCA in combination with fenbendazole for the best result. You can find more information on DCA usage here: DCA information. More information on fenbendazole and its potential therapeutic benefits for oncological diseases can be found here: https://www.fenbendazole.org/. The rest of the information can be found on google by using the keywords ‘‘fenbendazole cancer“. Hope this information helps.
Q: Hello. Can I take DCA while getting chemotherapy? I get 140mg of Abraxane per week for breast cancer. Maricel A: Dear Maricel, Thank you for your question. Yes, you can try taking Abraxane or Paclitaxel with DCA on the following conditions: • You currently do not suffer from pre-existing neuropathy, especially the one that was caused by previous chemotherapy, • You take a 3 day break from DCA and Alpha-lipoic acid before Abraxane or Paclitaxel injection, • You should resume DCA and Alpha-lipoic acid not sooner than 4 days after your last chemotherapy infusion, • You should resume your daily Vitamin B supplementation as soon as you’re released from the healthcare setting, There are studies, which prove that Sodium dichloroacetate can reverse the mitochondrial damage as well as dysfunction in Paclitaxel treated cancer cells. This reverses Abraxane/Paclitaxel drug resistance and makes the chemotherapy work more efficiently. On top of that, DCA itself causes apoptosis (natural cell death) in cancer, therefore, you receive a combined effect. You can see a comparison made by researchers that observed how well 1) Paclitaxel, 2) DCA and 3) Paclitaxel + DCA work on mice tumors below. (In vivo growth of tumors in mice treated with DCA alone or in combination with paclitaxel.) You can also find the study on DCA + Paclitaxel in the following link: Dichloroacetate restores drug sensitivity in paclitaxel-resistant cells by inducing citric acid accumulation. Hope you find this information useful, DCA Guide
Q: Dear Sir or Madam, I have a question about DCA, next week I start with immune therapy because I have lung cancer. Is it safe and can I still use DCA? Best regards, Alfredo. A: Dear Alfredo, thank you for your letter. We are getting similar questions often, therefore, we will try to explain DCA and immunotherapy in greater detail. In most cases, using Sodium dichloroacetate with checkpoint inhibitors such as pembrolizumab (Keytruda), atezolizumab (Tecentriq) and other similar drugs is a great option. It does not look that DCA could be unsafe with any type of immunotherapies. (Ref.) Immunotherapy helps the person’s own immune system fight against tumors. This class of medications is especially useful when the cancer develops resistance against conventional chemotherapy treatment. It also allows the immunity to bypass the special proteins that cancer cells develop as “camouflage” to continue growing and expanding. As the cancer progresses, it continues to develop an acidic environment around it. Lactic acid is considered an important factor in driving cell invasion, angiogenesis and immune suppression. Unfortunately, this process disables the immune system from fully engaging in tumor eradication. Furthermore, it diminishes the effectiveness of immunotherapy. The mechanism can be seen in the scheme below. (Ref.) It is proven that DCA successfully inhibits aerobic glycolysis in cancer. This decreases the massive amount of lactate secreted by the tumor cells and prevents acidosis. The surrounding extracellular space remains in normal pH, thus the immune system can recognize and destroy tumors more effectively. Considering everything, if you aim to efficiently treat cancer, Sodium dichloroacetate and immunotherapy can go hand in hand. These are the key points that you should keep in mind when using DCA alongside immunotherapy: • You should be free from peripheral neuropathy caused by previous chemotherapy treatment, • If you develop rare neurological complications from immunotherapy such as Guillan-Barre syndrome, encephalitis or any type of neuropathies, please stop DCA treatment until the side effects resolve, • Avoid using DCA, Vitamin B1 and Alpha-lipoic acid during your stay at the hospital while you’re receiving immunotherapy, you can resume DCA and supplements 2 days after you’re released from the healthcare setting, • If you’re receiving cytotoxic chemotherapy, such as platinum based compounds (cisplatin, carboplatin, oxaliplatin) or taxanes (paclitaxel, docetaxel) – avoid using DCA and Alpha-lipoic acid 3 days before hospitalisation and 7 days after receiving chemotherapy infusions. After that time period, if you haven’t developed chemotherapy induced peripheral neuropathy, you can continue using the DCA protocol as usual. Remember, DCA fights cancer on its own and can be used as monotherapy, but when it is incorporated with immunotherapy, the combination should work even stronger. (Ref.) Hope you find this information useful. Best regards, DCA Guide
Q: Can we use along with Keytruda/Pembrolizumab ? Jon D. A: Hello, Jon. Yes, DCA can be safely used with Keytruda (Pembrolizumab) as no drug-drug interactions are expected. (Ref.) As far as we heard from our own experience, there haven't been any bad interactions between Sodium dichloroacetate and biological therapy. Also, based on research and cancer biology facts, it seems that DCA and immunotherapy can go hand in hand. (Ref.) You can find more details in the previous answer that analyses Sodium dichloroacetate and immunotherapy in-depth. (32)
Q: Good Day, my Aunt has stage 4 colon cancer with metastasis. She is 5'7 and is weighing 140 pounds. Do you recommend starting DCA treatment and if so what dose should she take? Thank you. Isabel. A: Dear Isabel, thank you for your question. DCA therapy can help in almost every case of cancer, with varying degrees of success. The majority of people experience improvement in their symptoms, some have their disease stabilized and live without further cancer progression, and some even achieve remission thus remaining cancer-free. Nevertheless, stage IV colon cancer means that the tumors have spread in the body, this could make the treatment more difficult. Despite that, a clinical case published by Dr. A. Khan displays that DCA can be great for treating advanced colon cancer even when traditional medical treatments fail. You can read the study here: Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy. In the example of this 57-year-old woman, the stage IV colon cancer was stabilized with the help of Sodium dichloroacetate therapy and did not progress. It also did not cause any serious toxicity in the period of 4 years. The female remained highly functional and could continue running her own business, which proves that DCA treatment can be less debilitating than traditional chemotherapy. We could go on and on about the potential benefits of the Sodium dichloroacetate. To answer your question, we would recommend your aunt trying DCA. She can take it as a single treatment or combine it with the traditional chemotherapy (5-fluorouracil, oxaliplatin or irinotecan etc.) or immunotherapy (Avastin/bevacizumab). You can take DCA with Avastin without taking any breaks. However, when you‘re receiving chemotherapy – please make a two day break from DCA and Alpha-lipoic acid before getting chemotherapy and a three day break after receiving chemotherapy. Afterwards you can resume to taking the DCA protocol as usual. For your aunt, weighing 140 lbs, she should begin with 12,5 mg / kg a day. Take it for two weeks then do a one week break. This would mean that she takes one of the following: 1) 800 mg of DCA powder, 2) two 333 mg capsules with breakfast and one 333 mg capsule with dinner, 3) one 500 mg capsule with breakfast and one 500 mg capsule with dinner. If she tolerates DCA without any problems, she can move up to taking 25 mg / kg a day. Take it for two weeks, then take a week off. Repeat the cycles. Take one of the following: 1) 1600 mg of DCA powder, 2) three 333 mg capsules with breakfast and two 333 mg capsules with dinner, 3) two 500 mg capsules with breakfast and one 500 mg capsule with dinner. Don‘t forget to take the advice and supplements we describe here. Don't forget to take Vitamin B1 and Alpha-Lipoic acid with DCA just like we described. From our experience, we can tell that this is the biggest mistake some people tend to make. Here…
Q: Have you had proven positive results for AML? Leah A: Hello, Leah. Yes, however, these people that had AML also took traditional chemotherapy. Acute myeloid leukemia is an aggressive cancer that needs to be closely monitored by doctors, because it can cause anemia (which makes you weak), trombocytopenia (which makes you prone to bleeding) and, most importantly, it causes an impaired immune response (which makes you prone to catching infections). Therefore, we strongly advise every sufferer of acute myeloid leukemia to be monitored by their hematologist. Theoretically, DCA should be beneficial for every type of cancer. In some cases, drugs such as DCA can help you maintain a longer remission. Some medications like fenbendazole can mix pretty well with Sodium dichloroacetate in order to maintain a cancer-free time period. Sometimes, DCA can be the missing puzzle in the previous treatments that can finally help someone with AML achieve a lasting remission. The study explains instances like this in more detail: Perturbation of cellular oxidative state induced by dichloroacetate and arsenic trioxide for treatment of acute myeloid leukemia. Patients that cannot receive cytotoxic chemotherapy or have relapsed from remission could indeed benefit from the treatment of DCA. Blood cancers are a difficult subject, however, we hope that our answer sheds more light on your journey. Please don't hesitate to ask us more in case you have more questions.
Q: Hi, I wonder if any of the top rated DCA suppliers listed on your website can directly ship sodium DCA to mainland China. My aunt has been diagnosed with glioma three months ago, but her family refuses to use surgery or chemotherapy due to the concern over cost, lack of efficacy and severe side effects. She tried radiotherapy but the radiotherapy doesn't work well. So we thought to give DCA a try. Much appreciated if you can help me with my request. Thank you. Dan A: Hello, Dan. Yes, we believe that most of the listed DCA suppliers should be able shipping directly to China. The top two suppliers get orders from all over the world, including India, South Korea, Japan and so on. You can also try ordering it at Amazon: https://www.amazon.com/s/ref=nb_sb_noss?url=search-alias%3Daps&field-keywords=dca. We're glad that you've found this alternative solution, because we‘re aware of the limited choices today for treating gliomas. The most important clinical research on DCA for astrocytomas and glioblastomas discovered that Sodium dichloroacetate can be combined with all types of the possible treatments – surgery, radiotherapy and chemotherapy (in particular with Temozolomide). DCA is perfect for treating brain tumors as it is small enough to cross the blood-brain barrier and is truly safe in comparison with other treatments.
Q: Can you take this with high dose IV Vitamin C treatments? Daniel A: Hello, Daniel. We have followed hundreds of cases where people take DCA to treat their tumors and we noticed that a lot of people take Vitamin C additionally to their anti-cancer regimen. You should avoid self-medicating with high doses of Vitamin C perorally, because it will not enable you to achieve the concentrations needed to have any effect. The only way to do this correctly, is to have someone give you Vitamin C through intravenous injections. However, please be cautious. There are dangers. The biggest concerning side effect of high dose Vitamin C is oxalate crystal formation in the kidneys. This can happen after frequent Vitamin C administration in large quantities. We have found these rare cases in medical journals. One man has been taking huge doses of Vitamin C for a couple of years orally for thyroid cancer relapse prevention and after 2 years he experienced kidney damage due to oxalate crystal formation as a side product from Vitamin C. You should keep this risk in mind and stay alert. Regarding your question about DCA and high dose IV Vitamin C - we haven't heard any interactions and we firmly believe that this shouldn't cause a problem. Both treatments should be well tolerated and have no interactions with one another.
Q: Hello, my dear wife has been struggling with breast cancer and this site has been a great ray of hope. She has recently been put on a drug called Kisqali (ribociclib). Does anyone know if it is compatible with DCA? Or even complimentary? Do you know of any clinics/practices in Australia competent in administering this drug? I look forward very much to hearing from you. Richard. A: Hello, Richard. Unfortunately, Ribociclib (Kisqali) is quite a new therapy against breast cancer and we have found no studies, which discuss of combining it with DCA. However, we've reviewed the pharmacodynamics and pharmacokinetics of Ribociclib and it doesn't look like it should interact badly with Sodium dichloroacetate. In fact, as mentioned before, we have no bad experiences of combining DCA with targeted therapies. Please read carefully our work at DCA Information and learn all you need before administering DCA to your wife. Everything should be fine. Just don't overdose the DCA and remember that the protective supplements that we recommend with the DCA protocol are obligatory. DCA + Kisqali shouldn't cause any problems when used together. In fact, they could both provide benefits. Another therapy for breast cancer, Tamoxifen, has a synergistic effect with DCA. If you want real professional help, please contact Dr. Akbar Khan. He has a cancer center in Canada. He's one of the most famous oncologists who uses DCA with other conventional cancer treatments. We doubt that there is someone better in this field than him.
Q: Dear DCA guide, I am looking for support with guiding my mother (who is diagnosed with uveal melanoma, stage 3, mets) with start of using DCA. She already started ketogenic diet for some time, but now wants to add DCA with this. However we can't find any specialist/professional in our region. Can you help us out with this? Regards, Cees. A: Dear Cees, we would like to show you a really interesting study about melanoma + DCA Long-term stabilization of metastatic melanoma with sodium dichloroacetate. To make a long story short, a young man used DCA for a handful of years and it stabilized his melanoma, even shrunk the lymph node metastasis. He finally got better and afterwards added immunotherapy to the treatment. This was a great result, since the previous treatments prior to Sodium dichloroacetate had little to no effect. Your mother can definitely take DCA with Ketogenic diet for the treatment of Melanoma. It can stabilize as well as treat this type of skin cancer. Also consider talking with your oncologist, maybe he can add immunotherapy or targeted therapy to the picture for even better results. If you‘re clueless where to start with DCA, you can find a lot of information that you need to know about Sodium dichloroacate for free in our site. Please read it closely. Analysing DCA information is a must. Also, we advise you following your doctors advise, especially if he's offering biological therapy for melanoma. You can use the Ketogenic diet and DCA with the conventional treatment options. Regarding your question about specialists and medical professionals in Europe. There are many specialists and naturopathic clinics in Germany who prescribe Sodium dichloroacetate for cancer. However, we have no contact with them. You will need to find them yourself. If you have the funds and the time, you can try reaching out Dr. Akbar Khan in Canada. He's one of the best DCA oncologists in the world. You can find his site here at Medicor Cancer.